Extracellular vesicle cross-talk between pulmonary artery smooth muscle cells and endothelium during excessive TGF- β signalling: implications for PAH vascular remodelling

Excessive TGF- β signalling has been shown to underlie pulmonary hypertension (PAH). Human pulmonary artery smooth muscle cells (HPASMCs) can release extracellular vesicles (EVs) but their contents and signific...

Source: Cell Communication and Signaling - November 8, 2019 Category: Molecular Biology Authors: Fernando de la Cuesta, Ilaria Passalacqua, Julie Rodor, Raghu Bhushan, Laura Denby and Andrew H. Baker Tags: Research Source Type: research