Treating acne: What ingredients could help your skin?

The UK is spending millions on skincare products promising to improve acne - we spoke to the experts about what works and what doesn’t.
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news

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This article summarizes the milestones in the development of trifarotene leading to its first global approval for acne vulgaris.
Source: Drugs - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 9 November 2019Source: International Journal of PharmaceuticsAuthor(s): Mohammed Elmowafy, Khaled Shalaby, Hazim M. Ali, Nabil K. Alruwaili, Ayman Salama, Mohamed F. Ibrahim, Mohamed A. Akl, Tarek A. AhmedAbstractThe main objective of this study was to develop, characterize and evaluate the potential use of dapsone-loaded nanostructured lipid carriers (NLCs) as a topical treatment for acne. Differently charged NLC formulations were successfully prepared using an emulsification/sonication method. The particle sizes ranged from 106.2±5.6 nm to 151.3±7.4 nm, and the NLCs posses...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 9 November 2019Source: Materials Science and Engineering: CAuthor(s): I. Lacatusu, D. Istrati, N. Bordei, M. Popescu, A.M. Seciu, L.M. Panteli, N. BadeaAbstractPhytochemicals are priceless sources of bioactive compounds with multiple health benefices. The main objective of the current investigation was to develop nanostructured herbal formulations conditioned as appropriate hydrogel (HG) conferring an enhanced transdermal absorption of bioactive compounds from selective extracts and vegetable oils. The direct impact of research is represented by the identification of prototype products wh...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
Publication date: Available online 8 November 2019Source: Reproductive ToxicologyAuthor(s): Nis Brix, Lea L.B. Lauridsen, Andreas Ernst, Jørn Olsen, Tine B. Henriksen, Cecilia H. Ramlau-HansenAbstractWe explored whether maternal alcohol intake in early pregnancy is associated with pubertal timing in sons and daughters. In total, 15,819 children, born 2000–2003 within the Danish National Birth Cohort, gave half-yearly, self-reported information on pubertal development (Tanner stages, voice break, first ejaculation, menarche, acne, and axillary hair) from 11 years during 2012–2018. Information on maternal ...
Source: Reproductive Toxicology - Category: Toxicology Source Type: research
Condition:   Acne Vulgaris Interventions:   Radiation: 1,565nm NAFL;   Drug: Oral isotretinoin;   Other: Pricking blood therapy Sponsor:   xjpfW Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSION: Sequelae of acne at the onset of treatment reveal delayed indication of isotretinoin, which can have negative psychosocial impacts on quality of life. Isotretinoin should be indicated early to prevent this. Its use is supported by its lack of laboratory alterations and controllable adverse events. PMID: 31691769 [PubMed - in process]
Source: Sao Paulo Medical Journal - Category: General Medicine Authors: Tags: Sao Paulo Med J Source Type: research
ConclusionVariants rs10889677, rs2201841, and rs7517847 of IL ‐23R, and variant rs2243248 of IL‐4, showed strong associations with SAPHO syndrome. Patients carrying the A‐G‐C‐G‐T haplotype of IL‐23 are significantly more likely to develop SAPHO syndrome.
Source: International Journal of Rheumatic Diseases - Category: Rheumatology Authors: Tags: ORIGINAL ARTICLE Source Type: research
This article provides an overview about the current standard in the diagnosis of CS starting with clinical scores and screenings, the clinical signs, relevant differential diagnoses, the first-line biochemical screening, and ending with a few exceptional cases.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Background: Mobile medical applications (apps) for clinical management of medical conditions are increasing in prevalence. Our aim was to identify features and overall quality of acne apps that could facilitate clinical management. Methods: We established 10 pertinent features (6 essential and 4 desirable) for an acne app through literature search and nominal group discussion. Searches were then conducted in the Apple App Store and Google Play Store. Apps which assisted with clinical management of acne were assessed for functionality and quality. Overall quality was evaluated by grading against pre-established criteria for...
Source: Dermatology Online Journal - Category: Dermatology Source Type: research
CONCLUSION: People with acne need support to manage their condition effectively, particularly a better understanding of different topicals, how to use them and how to avoid side effects. Unrealistic expectations about the onset of action of treatments appears to be a common cause of frustration and non-adherence. Directing people towards accessible evidence-based information is crucial. PMID: 31701523 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research
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