MicroRNA ‐576‐5p enhances the invasion ability of trophoblast cells in preeclampsia by targeting TFAP2A

ConclusionOverexpression of miR ‐576‐5p and knockdown of TFAP2A may elevate cell proliferation and invasion of human trophoblast cells in vitro. Therefore, miR‐576‐5p may be used as a notable biomarker for the diagnosis, prevention, and treatment of PE. miR‐576‐5p targeting TFAP2A deserve further investigation in order to explore their potential role in PE.

Source: Molecular Genetics & Genomic Medicine - November 7, 2019 Category: Genetics & Stem Cells Authors: Xiaoning Wang, Shiyuan Peng, Kun Cui, Fangjuan Hou, Jie Ding, Ali li, Mingxia Wang, Li Geng Tags: ORIGINAL ARTICLE Source Type: research