Kidney damage and associated risk factors in rural and urban sub-Saharan Africa (AWI-Gen): a cross-sectional population study

Publication date: December 2019Source: The Lancet Global Health, Volume 7, Issue 12Author(s): Jaya A George, Jean-Tristan Brandenburg, June Fabian, Nigel J Crowther, Godfred Agongo, Marianne Alberts, Stuart Ali, Gershim Asiki, Palwende R Boua, F Xavier Gómez-Olivé, Felistas Mashinya, Lisa Micklesfield, Shukri F Mohamed, Freedom Mukomana, Shane A Norris, Abraham R Oduro, Cassandra Soo, Hermann Sorgho, Alisha Wade, Saraladevi NaickerSummaryBackgroundRapid epidemiological health transitions occurring in vulnerable populations in Africa that have an existing burden of infectious and non-communicable diseases predict an increased risk and consequent prevalence of kidney disease. However, few studies have characterised the true burden of kidney damage and associated risk factors in Africans. We investigated the prevalence of markers for kidney damage and known risk factors in rural and urban settings in sub-Saharan Africa.MethodsIn this cross-sectional population study (Africa Wits-International Network for the Demographic Evaluation of Populations and their Health Partnership for Genomic Studies [AWI-Gen]), we recruited unrelated adult participants aged 40–60 years from four rural community research sites (Nanoro, Burkina Faso; Navrongo, Ghana; Agincourt and Dikgale, South Africa), and two urban community research sites (Nairobi, Kenya; and Soweto, South Africa). Participants were identified and selected using random sampling frames already in use at each site. Participants co...
Source: The Lancet Global Health - Category: International Medicine & Public Health Source Type: research