Symptoms of mast cell activation syndrome in functional gastrointestinal disorders.

Symptoms of mast cell activation syndrome in functional gastrointestinal disorders. Scand J Gastroenterol. 2019 Nov 05;:1-4 Authors: Wilder-Smith CH, Drewes AM, Materna A, Olesen SS Abstract Objectives: Mast cell involvement is evident in functional gastrointestinal disorders (FGID). FGID and mast cell activation syndrome (MCAS) are associated with multi-organ symptoms. An overlap has not been assessed.Methods: MCAS symptoms were determined by questionnaires in 2083 FGID patients.Results: The median number of MCAS symptoms ([IQR] (range 0-16)) was 6 [4-8] in all FGID, and in functional dyspepsia (FD) patients, 7 [5-9] in overlapping irritable bowel syndrome and FD (IBS+FD), 5 [3-8] in IBS and 5 [3-6] in non-IBS/non-FD (p 
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

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Conclusions: Current studies analyzing the efficacy of hypnotherapy in FD provide encouraging data, but additional randomized controlled trials are needed before a firm position on the effectiveness of hypnosis in FD.
Source: American Journal of Therapeutics - Category: Drugs & Pharmacology Tags: Review Source Type: research
CONCLUSION: Overall, current evidence does not support an association between IBS and H. pylori infection. Further rigorous and detailed studies with larger sample sizes and after H. pylori eradication therapy are warranted. PMID: 31602169 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Tags: World J Gastroenterol Source Type: research
Gastrointestinal (GI) motility disorders are major contributing factors to functional GI diseases that account for>40% of patients seen in gastroenterology clinics and affect>20% of the general population. The autonomic and enteric nervous systems and the muscles within the luminal GI tract have key roles in motility. In health, this complex integrated system works seamlessly to transport liquid, solid, and gas through the GI tract. However, major and minor motility disorders occur when these systems fail. Common functional GI motility disorders include dysphagia, gastroesophageal reflux disease, functional dyspepsia...
Source: Cold Spring Harbor perspectives in medicine - Category: Research Authors: Tags: Bioelectronic Medicine TECHNIQUES Source Type: research
Publication date: Available online 10 August 2019Source: Journal of EthnopharmacologyAuthor(s): Timo A. Thumann, Eva-Maria Pferschy-Wenzig, Christine Moissl-Eichinger, Rudolf BauerAbstractEthnopharmacological relevance.Many medicinal plants have been traditionally used for the treatment of gastrointestinal disorders. According to the monographs published by the Committee on Herbal Medicinal Products (HMPC) at the European Medicines Agency, currently 44 medicinal plants are recommended in the European Union for the treatment of gastrointestinal disorders based on traditional use. The main indications are functional and chro...
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Authors: Kountouras J, Gavalas E, Doulberis M, Polyzos SA, Papaefthimiou A, Touloumtsi M, Vardaka E, Kountouras K, Papanikolopoulou K, Katsinelos P PMID: 31177649 [PubMed - as supplied by publisher]
Source: Journal of Neurogastroenterology and Motility - Category: Gastroenterology Tags: J Neurogastroenterol Motil Source Type: research
Functional gastrointestinal disorders are highly prevalent, cause significant suffering, and are costly to society. Pain is a central feature of 2 of the most common functional gastrointestinal disorders —irritable bowel syndrome and functional dyspepsia. Although these disorders have been well studied in adults, their etiology is poorly understood. We sought to identify early-life factors associated with development of abdominal pain in children (2–12 years old).
Source: Clinical Gastroenterology and Hepatology - Category: Gastroenterology Authors: Source Type: research
Emerging evidence that irritable bowel syndrome &functional dyspepsia are microbial diseases. Indian J Med Res. 2019 Apr;149(4):437-440 Authors: Talley NJ, Walker MM PMID: 31411166 [PubMed - in process]
Source: The Indian Journal of Medical Research - Category: Biomedical Science Authors: Tags: Indian J Med Res Source Type: research
CONCLUSIONS: In people with schizophrenia, but not in controls, CUD is associated with decreased risk of disorders of gut-brain interaction and inflammatory bowel disease, and possibly other serious disorders of the digestive organs. Our findings could lead to new targets for treatment and prevention of disorders of the digestive organs. PMID: 30880659 [PubMed - as supplied by publisher]
Source: Psychological Medicine - Category: Psychiatry Authors: Tags: Psychol Med Source Type: research
AbstractFunctional abdominal bloating and distension (FABD) are common gastrointestinal complaints, encountered on a daily basis by gastroenterologists and healthcare providers. Functional abdominal bloating is a subjective sensation that is commonly associated with an objective abdominal distension. FABD may be diagnosed as a single entity (the sole or cardinal complaint) or may overlap with other functional gastrointestinal disorders such as functional constipation, irritable bowel syndrome, and functional dyspepsia. The pathophysiology of FABD is not completely understood. Proposed underlying mechanisms include visceral...
Source: Advances in Therapy - Category: Drugs & Pharmacology Source Type: research
Abstract Gas, bloating, and belching are associated with a variety of conditions but are most commonly caused by functional gastrointestinal disorders. These disorders are characterized by disordered motility and visceral hypersensitivity that are often worsened by psychological distress. An organized approach to the evaluation of symptoms fosters trusting therapeutic relationships. Patients can be reliably diagnosed without exhaustive testing and can be classified as having gastric bloating, small bowel bloating, bloating with constipation, or belching disorders. Functional dyspepsia, irritable bowel syndrome, an...
Source: American Family Physician - Category: Primary Care Authors: Tags: Am Fam Physician Source Type: research
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