Vitamin D deficiency symptoms: A common symptom that could signal lack of the vitamin

VITAMIN D helps regulate the amount of calcium and phosphate in the body, a process that is needed to keep bones, teeth and muscles healthy. It is well understood that lacking the vitamin can cause bone problems but what people may not know is that it can also affect balance too.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news

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BCG stimulation promotes dendritic cell proliferation and expression of VDR and CYP27B1 in vitamin D‑deficient mice. Mol Med Rep. 2019 Oct 30;: Authors: Yang H, Zhang H, Li Y, Xiang L, Liu J Abstract Vitamin D deficiency may lead to an increased risk of tuberculosis. In the present study, the effects of Mycobacterium tuberculosis (Mtb) infection on dendritic cells (DCs) derived from vitamin D‑deficient mice or normal control mice were investigated. A vitamin D‑deficient mouse model was established, and bone marrow‑derived DCs (BMDCs) were isolated and treated with GM‑CSF and in...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
In conclusion, high-dose NR induces the onset of WAT dysfunction, which may in part explain the deterioration of metabolic health. Towards a Rigorous Definition of Cellular Senescence https://www.fightaging.org/archives/2019/11/towards-a-rigorous-definition-of-cellular-senescence/ The accumulation of lingering senescent cells is a significant cause of aging, disrupting tissue function and generating chronic inflammation throughout the body. Even while the first senolytic drugs capable of selectively destroying these cells already exist, and while a number of biotech companies are working on the productio...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
VITAMIN D deficiency can occur during the autumn and winter months when people don ’t get enough of the vitamin from sunlight, and left untreated, serious complications can occur. One symptom of the condition to watch out for may appear when going to the toilet.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Authors: Alshiyab DM, Al-Qarqaz FA, Heis LH, Muhaidat JM, Eddin WS, Atwan AA Abstract Background: Low vitamin D serum levels have been associated with many autoimmune disorders and several other skin diseases. Vitiligo is an autoimmune disease characterized by destruction of melanocytes by immune mechanisms. Melanocytes express vitamin D receptors, and their function can be affected by vitamin D status. Objectives: The main objective of this study is to compare vitamin D levels in patients with vitiligo vs normal population and whether vitamin D deficiency is associated with vitiligo. Methods: A case-contro...
Source: Dermatology Research and Practice - Category: Dermatology Tags: Dermatol Res Pract Source Type: research
Not long ago, vitamin D was riding high. Beyond its role in calcium homeostasis and bone health, animal studies linked vitamin D deficiency to numerous chronic illnesses including hypertension, diabetes, autoimmunity, and malignancy. Corroborating human observational studies reported associations between vitamin D deficiency and increased risks of hypertension, diabetes, cardiovascular disease, autoimmunity, and cancer. The lay press seized on this chorus of observational studies, testing of serum 25-hydroxyvitamin D levels proliferated, and supplementation with cholecalciferol (vitamin D3) and ergocalciferol (vitamin D2) ...
Source: JAMA - Journal of the American Medical Association - Category: General Medicine Source Type: research
AbstractNon-alcoholic fatty liver disease (NAFLD) is the most common liver disease which may progress to non-alcoholic steatohepatitis. The prevalence of sarcopenia, which is the loss of muscle mass and strength, is increasing in the aging society. Recent studies reported the relationship between NAFLD and sarcopenia. The skeletal muscle is the primary organ for glucose disposal. Loss of muscle mass can cause insulin resistance, which is an important risk factor for NAFLD. Moreover, obesity, chronic low-grade inflammation, vitamin D deficiency, physical inactivity, hepatokines, and myokines might be involved in the pathoph...
Source: Hepatology International - Category: Infectious Diseases Source Type: research
Abstract Vitamin-D deficiency is now recognized problem affecting multiple physiological functions. The aim of this study was to evaluate the effect of a single dose of vitamin D3injection on the inflammatory, muscular damage, metabolic and cardiovascular responses to an acute bout of resistance exercise (RE)in vitamin D-deficient resistance-trained males.Blood samples from 14 vitamin D-deficient resistance-trained males were obtained during two separate trials: lower vitamin-D (LVD) and higher vitamin-D (HVD, after vitamin D3injection). Metabolic, inflammatory, muscle damage and cardiovascular markers were evalua...
Source: The British Journal of Nutrition - Category: Nutrition Authors: Tags: Br J Nutr Source Type: research
In conclusion, our study demonstrates that chronic vitamin D deficiency or insufficiency reduced the size of skeletal muscle fibres, altered their composition, and decreased their oxidative potential. Most of the changes observed were reversible, either partially or completely, by restoring vitamin D to the diet of the deficient rats.
Source: The Journal of Steroid Biochemistry and Molecular Biology - Category: Biochemistry Source Type: research
Conditions:   Vitamin D Deficiency;   Aging Well Interventions:   Dietary Supplement: Vitamin D enriched (20 mcg/day) olive oil emulsion drink;   Dietary Supplement: Vitamin D enriched (20 mcg/day) coconut oil emulsion drink;   Dietary Supplement: Placebo coconut oil emulsion drink;   Dietary Supplement: Vitamin D supplement (20 mcg/day) Sponsors:   University College Dublin;   Department of Agriculture Food and the Marine Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Vitamin D deficiency is linked with poor muscle health in older adults, a new study finds.
Source: WebMD Health - Category: Consumer Health News Source Type: news
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