CEO of California's PGE says people who lost refrigerators full of food should visit "food banks," and thank him for "not burning down any houses”
(Natural News) There is ‘out of touch’ and there is outright tone-deafness, and the head of a large California power company just set the new standard for the latter. You may have heard that California energy company PG&E has been engaging in rolling blackouts for several weeks after the producer was blamed for several large,...
CONCLUSION: The origin of the poorer hearing of the better-hearing ear of SSD patients compared to an age-correlated NH cohort is still unclear. It is most likely a combination of different anatomical, immunological, etiological, and microcirculatory causes, which lead to poorer hearing of the better-hearing ear in SSD patients. PMID: 31705300 [PubMed - as supplied by publisher]
Abhiruchi Galhotra, Preeti SahuIndian Journal of Community Medicine 2019 44(4):299-302 Hearing is the key to learning spoken language, performing academically, and engaging socially for children. Degree of hearing loss quantifies the hearing ability from mild to profound, based on the audiometric findings for an individual across certain frequencies or pitches. Early identification and appropriate intervention is the prime need. A probable strategy is to ensure that every newborn is screened for possible hearing loss at the birth in the hospital. In India, hearing screening facility is mostly available to newborns brought...
ConclusionsIn children with syndromic hypoparathyroidism presented here, replacement therapy with rhPTH(1 –34) allowed to maintain adequate levels of the calcium and phosphate in the blood, normalize urinary calcium excretion, and reduce tetanic episodes. In patients with low compliance to conventional therapy or intestinal malabsorption, the use of rhPTH(1–34) could be considered, also to reduce th e side effects of treatment with vitamin D and calcium.
In conclusion, these data indicated that both A201T and I209T mutations disrupt Kir4.1 activity and are the cause of SeSAME/EAST-like syndrome in the siblings.
Conditions: Cochlear Implant; Hearing Disability; Hearing Disorders and Deafness Interventions: Device: Naida Hearing Aid; Device: Naida Contralateral Routing of Sound Device Sponsors: Ottawa Hospital Research Institute; Advanced Bionics Not yet recruiting
Keratitis-ichthyosis-deafness (KID) syndrome is a severe, untreatable condition characterized by ocular, auditory and cutaneous abnormalities, with major complications of infection and skin cancer. 86% of cases are caused by a heterozygous missense mutation (c.148G>A, p.D50N) in the GJB2 gene, encoding gap junction protein connexin 26 (Cx26), which alters gating properties of Cx26 channels in a dominant manner. We hypothesized that a mutant-allele-specific siRNA (AS-siRNA) could rescue the cellular phenotype in patient keratinocytes.
Recently, Jon Holmlund brought us up to date on an effort in Russia to proceed with CRISPR gene editing aimed at eliminating deafness. Coincidently, a recent MedPage article was posted regarding the ethics of using pre-implantation genetic diagnosis and IVF to purposefully select FOR an embryo with genetic deafness for a couple, both of whom … Continue reading "“Why did you make me this way?!”"
Should we use genetic testing to choose what type of children to bring into the world, and if so, how should we choose? Is it acceptable to choose a deaf child? Should we choose our children on the basis of non-disease traits such as intelligence if that were possible ? Does genetic selection put too […]
We examined neural responses of a group of Deaf signers who received access to signed input at varying ages to three linguistic phenomena at the levels of classifier signs, syntactic structure, and information structure. The amplitude of the N400 response to the marked word order condition negatively correlated with the age of acquisition for syntax and information structure, indicating increased cognitive load in these conditions. Additionally, the combination of behavioral and neural data suggested that late learners preferentially relied on classifiers over word order for meaning extraction. This suggests that late acqu...
Endocrine Practice, Ahead of Print.