Do not become iodine toxic

The post Do not become iodine toxic appeared first on Dr. William Davis.
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Wheat Belly Lifestyle hypothyroid iodine Source Type: blogs

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Hashimoto autoimmune thyroiditis (AIT) is the most common cause of acquired hypothyroidism in the pediatric population. Development of AIT is mediated mainly by cellular immune response directed toward thyroid autoantigens, leading to inflammation and impaired function of thyroid gland. Both thyroid dysfunction and inflammation affect the metabolism of plasma lipoproteins. The alterations in lipid profile worsen with the advancement of hypothyroidism, ranging from discrete changes in euthyroid AIT patients, to atherogenic dyslipidemia in the overt hypothyroidism. In this review, characteristics of dyslipidemia in pediatric...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Exp Clin Endocrinol Diabetes DOI: 10.1055/a-1062-6167Around 5–10% of hypothyroid patients continue to experience profound and sometimes disabling symptoms, including fatigue, depression and impaired cognition, in spite of being adequately replaced biochemically. The use of the combination of levothyroxine and liothyronine and natural desiccated thyroid extract is controversial for reasons of costs, a lack of evidence of additional benefit over levothyroxine alone, and potential safety concerns. Clinical guidelines caution against the use of both, and advise that only in exceptional cases may a short trial be consider...
Source: Experimental and Clinical Endocrinology and Diabetes - Category: Endocrinology Authors: Tags: Letter to the Editor Source Type: research
WS is diagnosed in a patient who presents with progressive neurologic symptoms including cerebellar ataxia, sensorineural hearing loss, hyposmia, and OA against a background of type I DM, central DI, hypothyroidism, and hydronephrosis.
Source: Neurology Clinical Practice - Category: Neurology Authors: Tags: All Clinical Neurology, Clinical neurology examination, All Movement Disorders, Gait disorders/ataxia, Mitochondrial disorders Case Source Type: research
Dana Carpender, friend and author of many low-carb cookbooks, provided this review of my new Revised &Expanded Wheat Belly, below. For more of Dana’s signature wit and conversation, you can join her on her engaging Facebook page “Hold the toast press” or visit her Amazon page that lists all her wonderful low-carb cookbooks. It’s funny how things happen. Nine years ago I had already been eating a low carbohydrate diet for 16 years. During that time I had occasionally eaten low carb tortillas and low carb bread. These things were hardly a staple of my diet, but I kept ’em around for the occ...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Open autoimmune joint pain wheat belly Source Type: blogs
Authors: Sitoris G, Veltri F, Kleynen P, Cogan A, Belhomme J, Rozenberg S, Pepersack T, Poppe K Abstract Backgound: Subclinical hypothyroidism (SCH) and thyroid autoimmunity (TAI) have been associated with poor clinical pregnancy outcomes. However, these outcomes also depend on a number of demographic and obstetric variables. Therefore, the aim of the study was to investigate the impact of thyroid disorders on these outcomes, after adjustment for associated demographic and obstetrical parameters. METHODS: Cross-sectional study including 1521 pregnant women who did their work-up and follow-up in our center and h...
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
Authors: Fang L, Xu Z, Lu J, Hong L, Qiao S, Liu L, An J Abstract Hypothyroidism is associated with profound left ventricular dysfunction. Triiodothyronine (T3) supplementation may improve cardiac function after ischemic reperfusion (I/R) injury. In the present study, the effect of T3 on major calcium cycling proteins and high-energy phosphate content during I/R was evaluated. Isolated perfused rat hearts were divided into 5 groups: Sham Control (Sham, n=10), Control (n=8), T3 10 nM (T3-10, n=10), T3 25 nM (T3-25, n=10) and T3 50 nM (T3-50, n=10). T3 was administrated for 60 min before 30 min of ischemia and 120 mi...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
The objective of this study was to collect drinking water from water treatment plants nationally and test if water iodine concentration (WIC) correlated to urinary iodine concentration (UIC) of school-aged children in a national survey 2007 to former goitre frequency in 1929 and to thyroid volume data in 2007.MethodsIn 2012, 166 treatment plants, located in 57% (166 of 290) of all Swedish municipalities, were asked to collect drinking water samples of approximately 10 ml. In 2007, tap water samples of the same volume were collected from 30 randomly selected schools for the national survey. Analysis of WIC was done in both ...
Source: Environmental Health and Preventive Medicine - Category: Environmental Health Source Type: research
Authors: Gupta R, Sharma KK, Soni S, Gupta N, Khedar RS Abstract Background: Hypertension is highly prevalent in India but frequency of resistant hypertension has not been well studied. Methods: We performed a registry-based study at a single center in patients with primary diagnosis of hypertension (n=3073). Details of co-morbidities, medications and blood pressure (BP) control were obtained. Patients with coronary heart disease, cerebrovascular disease and chronic kidney disease were excluded. Resistant hypertension was defined as uncontrolled hypertension (BP ≥140/90) with use of 3 drugs of which one was ...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Authors: Admati I, Wasserman-Bartov T, Tovin A, Rozenblat R, Blitz E, Zada D, Lerer-Goldshtein T, Appelbaum L Abstract The thyroid hormones (THs) T3 and T4 are crucial regulators of brain development and function. Cell-specific transporter proteins facilitate TH uptake and efflux across the cell membrane, and insufficient TH transport causes hypothyroidism and mental retardation. Mutations in the TH transporters monocarboxylate transporter 8 (MCT8, SLC16A2) and the organic anion-transporting polypeptide 1C1 (OATP1C1, SLCO1C1) are associated with the psychomotor retardation Allan-Herndon-Dudley syndrome (AHDS) and j...
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
CONCLUSIONS: Our results demonstrate that glis3, within the SHH pathway, appears to determine the number of endodermal cells committed to a thyroid fate. This is the first evidence of the involvement of glis3 in TD, increasing our knowledge on the genetic bases of CH pathogenesis. PMID: 31797737 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
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