Effects of Permissive Hypercapnia on Laparoscopic Surgery for Rectal Carcinoma.

Effects of Permissive Hypercapnia on Laparoscopic Surgery for Rectal Carcinoma. Gastroenterol Res Pract. 2019;2019:3903451 Authors: Wang L, Yang L, Yang J, Shan S Abstract Background: Permissive hypercapnia has been recommended during the treatment of chronic diseases; however, there are insufficient clinical data to investigate the feasibility of permissive hypercapnia in relatively long-term surgeries such as laparoscopic surgery for rectal carcinoma. This prospective study is aimed at investigating the efficacy and safety of permissive hypercapnia under different CO2 pneumoperitoneum pressures during the laparoscopic surgery for rectal carcinoma. Methods: A total of 90 patients undergoing laparoscopic surgery for rectal carcinoma were recruited from July 2016 to March 2017. They were randomly assigned to high hypercapnia group (n = 30), low hypercapnia group (n = 30), or control group (n = 30), whose PaCO2 levels were maintained at 56-65 mmHg, 46-55 mmHg, or 35-45 mmHg, respectively. The primary endpoint was peak pressure. Plateau pressure, dynamic compliance, arterial blood analysis, and hemodynamic measures were collected as secondary outcomes. Adverse events were monitored. Results: High hypercapnia group were reported to be associated with significantly lower peak pressure and plateau pressure, but higher dynamic compliance compared to low hypercapnia and control group (all P
Source: Gastroenterology Research and Practice - Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research

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Source: Case Reports in Gastroenterology - Category: Gastroenterology Source Type: research
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Source: Arab Journal of Gastroenterology - Category: Gastroenterology Source Type: research
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Source: Surgical Endoscopy - Category: Surgery Source Type: research
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Source: Hand Surgery - Category: Surgery Authors: Tags: Surg Endosc Source Type: research
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Source: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques - Category: Surgery Tags: Review Articles Source Type: research
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Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
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Source: Surgical Endoscopy - Category: Surgery Source Type: research
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