Loss-of-function phenotype of a PKC θT219A knockin mouse strain

Protein kinase C θ has been established as an important signaling intermediate in T-effector-cell activation and survival pathways by controlling activity of the key transcription factors NF-κB and NFAT. Previ...

Source: Cell Communication and Signaling - November 6, 2019 Category: Molecular Biology Authors: Nikolaus Thuille, Kerstin Siegmund, Victoria Klepsch, Jacqueline Sch örgenhuber, Sarah Danklmaier, Michael Leitges and Gottfried Baier Tags: Research Source Type: research