ENST00000489707.5 Is a Preferred Alternative Splicing Variant of PTK7 in Adrenocortical Cancer and Shows Potential Prognostic Value.

CONCLUSIONS ENST00000489707.5 is a preferred alternative splicing product of PTK7, with a significantly increased proportion in ACC compared with other cancers. Its expression shows potential prognostic value in terms of PFS and DSS in ACC patients. The methylation status of cg20819617 might play a critical role in modulating PTK7 transcription and ENST00000489707.5 expression. PMID: 31689287 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31689287?dopt=Abstract

Source: Medical Science Monitor - November 8, 2019 Category: Research Tags: Med Sci Monit Source Type: research