Effect of Renal Dysfunction on the Risks for Ischemic and Bleeding Events in Patients with Atrial Fibrillation Receiving Percutaneous Coronary Intervention

There is a paucity of studies exploring whether the ischemia-bleeding trade-off could be different according to the stages of renal dysfunction in patients with atrial fibrillation (AF) who underwent percutaneous coronary intervention (PCI). Among 19598 patients in a pooled database from 3 Japanese PCI studies (CREDO-Kyoto Cohort-2, RESET, and NEXT), 1547 patients had concomitant AF. Patients were divided into 4 groups according to their renal function (Creatinine clearance [CCr]>60 mL/min: N=703, 60 ≥ CCr>30 mL/min: N=627, CCr ≤30 mL/min: N=126, Dialysis: N=91).

Source: The American Journal of Cardiology - November 6, 2019 Category: Cardiology Authors: Ko Yamamoto, Hiroki Shiomi, Takeshi Morimoto, Masahiro Natsuaki, Yasuaki Takeji, Hirotoshi Watanabe, Yusuke Yoshikawa, Yukiko Matsumura-Nakano, Satoshi Shizuta, Kengo Tanabe, Kenji Ando, Kazushige Kadota, Yoshihiro Morino, Ken Kozuma, Yoshihisa Nakagawa, Source Type: research