Curcumin co-treatment ameliorates resistance to gefitinib in drug- resistant NCI-H1975 lung cancer cells.
CONCLUSION: Co-treatment of curcumin and gefitinib significantly improves the ability of gefitinib to inhibit cell proliferation, suppress the clonogenic capacity and enhance apoptosis in NCI-H1975 cells, and these effects are possibly mediated via a decrease in phosphorylation of proteins in downstream pathways of the epidermal growth factor receptor.
PMID: 31682378 [PubMed]
Source: Journal of Traditional Chinese Medicine - Category: Complementary Medicine Authors: Jin X, Wang J, Shen H, Ran R, Xu K, Zhang W, Tong X, Feng L Tags: J Tradit Chin Med Source Type: research
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