Awake craniotomy in a super obese patient using high flow nasal cannula oxygen therapy (HFNC).
This article presents a super obese patient (BMI 57 kg/m2) with drug-refractory epilepsy and obstructive sleep apnea who underwent left anterior temporal lobectomy through awake craniotomy to preserve language and memory, using warmed humidified high flow nasal cannula (HFNC) oxygen therapy. Awake craniotomy was facilitated by the use of HFNC, which proved essential to prevent airway collapse by creating continuous positive airway pressure through high flow and facilitated intraoperative neurologic language and memory testing while maintaining adequate oxygenation. PMID: 31686115 [PubMed - as supplied by publisher]
Conditions: Apnea, Obstructive Sleep; Obesity Intervention: Device: Bioelectrical Impedance Analysis (BIA) Sponsor: Samuel Lunenfeld Research Institute, Mount Sinai Hospital Recruiting
Conditions: Obesity; NAFLD Interventions: Biological: NGM395; Other: Placebo Sponsor: NGM Biopharmaceuticals, Inc Not yet recruiting
Conditions: Overweight; Obesity Intervention: Drug: Semaglutide Sponsor: Novo Nordisk A/S Not yet recruiting
Condition: Insomnia Intervention: Behavioral: Su-Man formula massage oil Sponsor: China Medical University Hospital Completed
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Condition: Adolescent Problem Behavior Intervention: Behavioral: Group/Cohort 2: PAP Sponsors: Association Tunisienne d'Etude&de Recherche sur l'Ath érosclérose; Biochimie Clinique LR99ES11; Department of Biochemistry, La Rabta Hospital, Tunisia.; Université de Toulon Not yet recruiting
This study provides a possible reason why genes carrying health risks have persisted in human populations. The second found evidence for multiple variants in genes related to ageing that exhibited antagonistic pleiotropic effects. They found higher risk allele frequencies with large effect sizes for late-onset diseases (relative to early-onset diseases) and an excess of variants with antagonistic effects expressed through early and late life diseases. There also exists other recent tangible evidence of antagonistic pleiotropy in specific human genes. The SPATA31 gene has been found under strong positive genomic sele...
Conclusion: OSA is common comorbidity in uncontrolled asthmatic children that is difficult to be screening using known scores as SCR and Brouilette score.
In this study, we aimed to assess vPSG findings in consecutive patients with a clinical diagnosis of NREM-parasomnia covering the whole phenotypic spectrum. Five hundred and twelve patients with a final diagnosis of NREM parasomnia who had undergone vPSG were retrospectively identified. vPSGs were analysed for features of NREM parasomnia and for the presence of other sleep disorders. Two hundred and six (40.0%) patients were clinically diagnosed with sleepwalking, 72 (14.1%) with sleep terrors, 39 (7.6%) with confusional arousals, 15 (2.9%) with sexsomnia, seven (1.4%) with sleep-related eating disorder, 122 (23.8%) with m...
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