Lung Cancer Rates Among Women Are Falling Much Slower Than Those in Men. Here ’s Why

Gina Hollenbeck said she did “everything right.” The Tennessee nurse and mother of two avoided cigarettes all her life. She ate organic food. She ran half marathons and played competitive tennis. But in 2015, she developed a persistent cough and rapidly lost weight. She didn’t have a primary-care doctor, so she consulted several specialists. For months, none could identify what was wrong. Finally, she paid out of pocket for chest X-rays and took them to an emergency room, where she was referred to a pulmonologist who diagnosed her with advanced lung cancer. “I was like, ‘This is a cruel joke,'” says Hollenbeck, who is now 42 and still not in remission. “Everybody kept saying, ‘There’s no way that you could possibly have lung cancer.'” Hollenbeck represents a worrying caveat to what is otherwise a great success for the U.S. medical system. Overall lung-cancer rates have fallen significantly in recent decades–but women, who have traditionally smoked less than men and thus developed and died from lung cancer less often, now account for a disproportionately high number of diagnoses. Lung cancer is the deadliest form of cancer in the U.S. But mortality rates have been falling for decades, driven by medical advances and historic decreases in cigarette smoking. The benefits, however, have not been shared equally. What was historically a men’s disease is now disproportionately affecting women. A 2018 study in th...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Cancer Source Type: news

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E-cigarettes may be more harmful to a smoker’s heart than traditional tobacco cigarettes. That’s the finding of new research from Cedars-Sinai Medical Center in Los Angeles, presented today (Nov. 11) at an American Heart Association scientific conference. The Cedars-Sinai team compared the hearts of 10 non-smokers to the hearts of 10 tobacco smokers and 10 e-cigarette smokers. All the people in the study were younger than 40, and all were otherwise healthy. In response to a mild bout of exercise, measures of blood flow increased in the hearts of the non-smokers. Among the tobacco smokers, this increase was blun...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized embargoed study heart health vaping Source Type: news
Rationale: Anlotinib, a novel orally administered multitargeted tyrosine kinase inhibitor, inhibiting tumor angiogenesis and growth, significantly prolonged overall survival, and progression-free survival with a manageable safety profile as a third-line therapy among refractory advanced nonsmall cell lung cancer (NSCLC) patients in ALTER 0303 trail (NCT02388919). Patient concerns: Two squamous cell lung cancer patients with mediastinal metastasis undergoing the treatment of anlotinib developed clinical symptom of cough, which was worse upon ingestion. Diagnoses: On the basis of patients’ clinical symptoms and...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Publication date: Available online 14 October 2019Source: Pulmonary Pharmacology &TherapeuticsAuthor(s): Huda Badri, Jaclyn A. SmithAbstractCough is mediated by vagal afferent fibres innervating the larynx and proximal airways. Pre-clinical studies suggest that vagal C fibres produce Substance P, one of the tachykinin family of neuropeptides, which has been shown to enhance cough via the neurokinin-1 (NK-1) receptor and studies in animal models have also shown that NK-1 antagonists are effective at blocking induced cough. In the past, tachykinin receptor antagonists have yielded disappointing results in treating asthma...
Source: Pulmonary Pharmacology and Therapeutics - Category: Respiratory Medicine Source Type: research
Conclusion: Data from our study suggest nivolumab is well-tolerated and effective in Indian patients with recurrent advanced NSCLC after failure of the multiple first lines of platinum-based combination chemotherapy.
Source: Indian Journal of Cancer - Category: Cancer & Oncology Authors: Source Type: research
LUNG cancer can start in any part of the lungs or airways. The symptoms tend to develop as the condition progresses. It ’s extremely important to recognise any signs as early as possible and noticing the following five signs in your cough could be a warning.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Systematic reviews and guidelines are available to guide management of cough in lung cancer, but evidence for intervention efficacy is limited, and little research has yet described current practice.
Source: Collegian - Category: Nursing Authors: Source Type: research
Conclusion: DAC may exert an anti-cancer effect, which can lead to tumor regression. This is supposed to be achieved by the combined DAC's immunomodulatory, anti-angiogenic, anti-metastatic, anti-proliferative, and pro-apoptotic effects mediated through multiple signaling pathways. We propose that DAC can be used as a complementary medicine to prolong the life expectancy and improve the life quality of SCLC patients. PMID: 31561410 [PubMed - in process]
Source: Medicina (Kaunas) - Category: Universities & Medical Training Authors: Tags: Medicina (Kaunas) Source Type: research
Smoke-measuring smart shirts, breath sound analyzing algorithms, and smart inhalers pave the way of pulmonology and respiratory care into the future. As the number of patients suffering from asthma, COPD, or lung cancer due to rising air pollution and steady smoker-levels will unfortunately not decrease any time soon, we looked around what technology can do to help both patients and caregivers. The results are breathtaking. Attacks of breathlessness are too common The diseases which pulmonologists and respiratory care specialists attempt to fight are among the most common conditions in the modern world – and t...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Artificial Intelligence Future of Medicine Health Sensors & Trackers AI asthma cancer cancer treatment care COPD diagnostics inhaler lung lung cancer management medical specialty pulmonology respiratory respiratory care Source Type: blogs
This article reviews the research and application of antioxidant therapy in RILI. 
 DOI: 10.3779/j.issn.1009-3419.2019.09.05
Source: Chinese Journal of Lung Cancer - Category: Cancer & Oncology Source Type: research
Publication date: Available online 29 August 2019Source: Respiratory Medicine Case ReportsAuthor(s): Petros Oikonomidis, Fotios Fousekis, Panagiotis Kotsaftis, Ioannis Pilios, Dionysios Dimas, Georgios GiannoulisAbstractPulmonary actinomycosis is a rare infectious disease, which is characterized by a wide range of symptoms and no specific imaging findings and may be confused with neoplasia, tuberculosis or pneumonia. Endobronchial involvement of actinomycosis may be caused by aspiration of foreign bodies or broncholithiasis and may bronchoscopically masquerade as malignancy. A case of 68-year-old man is reported, who prese...
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
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