Methods for the early detection of drug-induced pancreatitis: a systematic review of the literature

Review of 59 studies found minimal evidence to support the use of serial monitoring by ultrasound or pancreatic enzymes to detect cases of drug-induced pancreatitis (DIP). Authors recommend greater uptake of standardised diagnostic and causality criteria for DIP is needed.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news

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Conclusions In a meta-analysis of randomized trials comparing EUS-BD to conventional biliary drainage modalities, no difference in technical or clinical success was observed. Importantly, EUS-BD was associated with decreased risks of stent/catheter dysfunction when compared to both PTBD and ERCP, and decreased post-procedure pancreatitis when compared to ERCP, suggesting the potential role for EUS-BD as an alternative first-line therapy in distal malignant biliary obstruction. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract&...
Source: Endoscopy International Open - Category: Gastroenterology Authors: Tags: Original article Source Type: research
Publication date: November 2019Source: Journal of the American College of Radiology, Volume 16, Issue 11, SupplementAuthor(s): Expert Panel on Gastrointestinal Imaging, Kristin K. Porter, Atif Zaheer, Ihab R. Kamel, Jeanne M. Horowitz, Hina Arif-Tiwari, Twyla B. Bartel, Mustafa R. Bashir, Marc A. Camacho, Brooks D. Cash, Victoria Chernyak, Alan Goldstein, Joseph R. Grajo, Samir Gupta, Nicole M. Hindman, Aya Kamaya, Michelle M. McNamara, Laura R. CarucciAbstractAcute pancreatitis (AP) is divided into two types: interstitial edematous and necrotizing. AP severity is classified clinically into mild, moderately severe, and sev...
Source: Journal of the American College of Radiology - Category: Radiology Source Type: research
Acute pancreatitis (AP) is divided into two types: interstitial edematous and necrotizing. AP severity is classified clinically into mild, moderately severe, and severe, depending on the presence and persistence of organ failure and local or systemic complications. The revised Atlanta classification divides the clinical course of AP into an early (first week) and late phase (after first week) and the clinical phase determines the role of imaging. Imaging has a limited role in the early phase. In the early phase with typical presentations of AP, ultrasound is usually the only appropriate modality and is used for the detection of gallstones.
Source: Journal of the American College of Radiology : JACR - Category: Radiology Authors: Tags: Appropriate use criteria Source Type: research
Authors: Pagliari D, Saviano A, Brizi MG, Mancarella FA, Cannone F, Musso M, Franza L, Attili F, Gasbarrini A Abstract OBJECTIVE: Cannabis is an illegal drug that has been under the spotlight in recent years, due to its vast array of effects on different biological systems. The role of cannabis has been investigated in the management of pain in acute pancreatitis (AP), even though some studies suggest that it may have a causative effect in this pathology and could be considered the underlying etiology in some cases of idiopathic AP. In this case report, we discuss the case of a young man who presented with three di...
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Authors: Liu L, Huang X, Li X, Ma L, Zhao X, Yang X Abstract PURPOSE: To investigate the diagnostic value of ultrasound combined with computed tomography (CT) in pancreatic cancer. METHODS: 312 patients with pancreatic lesions treated in the Affiliated Hospital of Qingdao University were retrospectively analyzed, including 217 patients definitely diagnosed with pancreatic cancer and 95 patients diagnosed with pancreatitis. A hundred and one patients with ultrasonic diagnosis were enrolled into the ultrasound group, 98 patients with CT diagnosis were enrolled into CT group, and 113 patients undergoing ultrasound...
Source: Journal of B.U.ON. - Category: Cancer & Oncology Tags: J BUON Source Type: research
ConclusionsStatins exert a beneficial role in preventing acute pancreatitis in patients with pancreatic cysts undergoing endoscopic ultrasound-guided fine-needle aspiration. If confirmed in prospective trials, our findings may pave the way to an extensive use of statins as prophylactic agents in pancreatic interventional endoscopy.
Source: Hepatobiliary and Pancreatic Diseases International - Category: Gastroenterology Source Type: research
Conclusion EUSGBD demonstrated better clinical success than ETGBD and PCGBD in the management of acute cholecystitis patients at high surgical risk. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Endoscopy - Category: Gastroenterology Authors: Tags: Original article Source Type: research
Histologic diagnosis of autoimmune pancreatitis (AIP) using endosonographic ultrasound-guided fine-needle aspiration (EUS-FNA) is difficult. To address this issue, new fine-needle biopsy (FNB) needles were recently developed. Here, we prospectively evaluated 2 newly designed EUS-FNB needles for histologic evaluation in patients with type 1 AIP.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Source Type: research
Conclusion Primary EUS-BD is an effective treatment with few AE. Comparing EUS-BD versus ERCP, EUS-BD has comparable efficacy and improved safety as a primary treatment for malignant biliary obstruction. Further randomized trials should be performed to identify patient populations and clinical scenarios in which primary EUS-BD would be most appropriate. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text
Source: Endoscopy International Open - Category: Gastroenterology Authors: Tags: Original article Source Type: research
Conclusions: Our study is the first to report that endoscopic therapy of PFCs using LAMS is safe and effective even in a community hospital setting with limited resources and support compared to large academic centers. PMID: 31615198 [PubMed - as supplied by publisher]
Source: Clinical Endoscopy - Category: Gastroenterology Tags: Clin Endosc Source Type: research
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