Infectious Diseases A--Z: Can the measles virus cause immune memory loss?
Measles infection can greatly reduce acquired immune memory, according to a new study. Acquired immune memory is when a person's immune system attacks foreign invaders and can remember how to fight the dangerous antigens in the future. "Measles virus infects immune cells, particularly long-term immune memory cells, causing immune "'amnesia'" which can last for varying amounts of time," [...]
Getting measles is even more dangerous than doctors had realized, because it destroys immunity that the individual has acquired to other diseases, researchers said on Thursday.Reuters Health Information
Getting measles is even more dangerous than doctors had realized, because it destroys immunity that the victim has acquired to other diseases, researchers said on Thursday.
New research shows the virus can have devastating effects on the immune system that persist much longer than the illness itself.
The virus can cause 'immune amnesia' which shifts our defences back to a 'baby-like' state.
A measles infection can cripple a child's immunity against viruses and bacteria for the long-term, leaving them more vulnerable to future infections.
Not so long ago, coming down with measles was seen almost as a rite of passage. Before measles vaccination began in the U.S. in the early 1960s, millions of Americans, many of them children, contracted the virus each year—forcing them to weather a flu-like illness and telltale skin rash, but also bestowing lifelong immunity. As a result, some Americans still view measles as relatively harmless—which, in addition to a dangerous uprising of anti-vaccine sentiment, has led some parents to decline shots for their children, contributing to a resurgence of preventable illness in the U.S. and overseas. A pair of relat...
Study reveals how measles infection reduces protection against other diseases
Thakkar and McCarthy suggest that periodicity in measles incidence artifactually drives our estimates of a 2- to 3-year duration of measles "immune-amnesia." We show that periodicity has a negligible effect relative to the immunological signal we detect, and demonstrate that immune-amnesia is largely undetectable in small populations with large fluctuations in mortality of the type they use for illustration.
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In this study, we show that calorie restriction is protective against age-related increases in senescence and microglia activation and pro-inflammatory cytokine expression in an animal model of aging. Further, these protective effects mitigated age-related decline in neuroblast and neuronal production, and enhanced olfactory memory performance, a behavioral index of neurogenesis in the SVZ. Our results support the concept that calorie restriction might be an effective anti-aging intervention in the context of healthy brain aging. Greater Modest Activity in Late Life Correlates with Lower Incidence of Dementia ...