Umbilical Cord Blood Stearoyl-CoA Desaturase index and Lipoprotein Lipase Mass Level in Small-for-Gestational Age Newborns

Stearoyl-CoA desaturase (SCD) is a rate limiting enzyme in converting saturated fatty acids (palmitic acid [16:0] and stearic acid [18:0]) to monounsaturated fatty acids (palmitoleic acid [16:1 (n-7)] and oleic acid [18:1 (n-9)]) in the cell, respectively, and is associated with de novo lipogenesis (DNL). [1] SCD index is known as a surrogate marker for DNL. There are some published studies on SCD index in children, [2-6] however, studies on SCD index in neonates are limited. [7]

Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - November 5, 2019 Category: Biomedical Science Authors: Kazumasa Fuwa, Nobuhiko Nagano, Yohei Kitamura, Fujihiko Iwata, Tomoo Okada, Ichiro Morioka Source Type: research