ABO Genotype and Blood Type Are Associated with Otitis Media

Genetic Testing and Molecular Biomarkers,Volume 23, Issue 11, Page 823-827, November 2019.
Source: Genetic Testing and Molecular Biomarkers - Category: Genetics & Stem Cells Authors: Source Type: research

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Luc's abscess is a rare complication of acute otitis media, with a challenging diagnosis and a controversial surgical treatment. The aim of the present study was to review the published literature in order to clarify the clinical features and the surgical management of those patients.
Source: Auris, Nasus, Larynx - Category: ENT & OMF Authors: Source Type: research
Conclusions Despite being a rare condition, Gradenigo syndrome should be taken into account as potential differential diagnosis in children referred to emergency department for recurrent headache and strabismus. An accurate anamnesis to document recent ear infection is mandatory to orientate the diagnosis and focus radiological investigations. Early recognition and timely intervention may allow conservative management to succeed, avoiding the need for surgery and serious sequelae.
Source: Pediatric Emergency Care - Category: Emergency Medicine Tags: Illustrative Cases Source Type: research
Purpose of review WHIM syndrome (warts, hypogammaglobulinemia, immunodeficiency, myelokathexis, or WHIMs) is a very rare autosomal dominant immunodeficiency disorder attributable to mutations in CXCR4. We reviewed clinical manifestations in 24 patients in 9 families to expand understanding of this syndrome. Recent findings Warts, cellulitis and respiratory infections are common in patients with WHIMs. Less commonly these patients have congenital heart disease, human papilloma virus-associated malignancies (cervical and vulvular) and lymphomas. Hearing loss because of recurrent otitis media is another important complic...
Source: Current Opinion in Hematology - Category: Hematology Tags: MYELOID BIOLOGY: Edited by David C. Dale Source Type: research
Conclusion: According to WHO-recommended thresholds for interpreting cost-effectiveness, introduction of PCV-13 for children under 5 years in the Islamic Republic of Iran would be cost-effective. PMID: 31774134 [PubMed - in process]
Source: Eastern Mediterranean Health Journal - Category: Middle East Health Tags: East Mediterr Health J Source Type: research
CONCLUSION: Combined data from 11 hospital and community-based studies of children aged less than 18 years who lived in communities with a high burden of acute and chronic respiratory illness showed that RSV was second only to HRV as the most prevalent virus detected across all settings. RSV was the most frequently detected virus in infants hospitalised with bronchiolitis, including those aged less than 6 months. In contrast, RSV was uncommonly detected in children in community settings. In northern Australia, effective maternal and infant RSV vaccines could substantially reduce RSV bronchiolitis-related hospitalisations, ...
Source: Rural and Remote Health - Category: Rural Health Tags: Rural Remote Health Source Type: research
Abstract OBJECTIVE: To investigate hearing thresholds in children born with cleft palate and in children with otitis media with effusion but no cleft palate. DESIGN: Prospective longitudinal group comparison study. SETTING: University hospital. PARTICIPANTS: Sixteen children born with nonsyndromic cleft palate with or without cleft lip (CP±L) and 15 age-matched children with otitis media with effusion (OME) but without cleft. MAIN OUTCOME MEASURES: Hearing was tested at repeated occasions beginning with neonatal auditory brainstem response (ABR) at 1-4 months of age, and age-appropriate ...
Source: The Cleft Palate-Craniofacial Journal - Category: ENT & OMF Authors: Tags: Cleft Palate Craniofac J Source Type: research
A comprehensive understanding about the pathogenesis of otitis media (OM), one of the most common pediatric diseases, has the potential to alleviate a substantial disease burden across the globe. Advancements in genetic and bioinformatic detection methods, as well as a growing interest in the microbiome, has enhanced the capability of researchers to investigate the interplay between host genes, host microbiome, invading bacteria, and resulting OM susceptibility. Early studies deciphering the role of genetics in OM susceptibility assessed the heritability of the phenotype in twin and triplet studies, followed by linkage stu...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
In this study, we focus on recognizing normal, AOM, CSOM, and earwax tympanic membrane (TM) conditions using fused fine-tuned deep features provided by pre-trained deep convolutional neural networks (DCNNs). These features are applied as the input to several networks, such as an artificial neural network (ANN), k-nearest neighbor (k NN), decision tree (DT) and support vector machine (SVM). Moreover, we release a new publicly available TM data set consisting of totally 956 otoscope images. As a result, the DCNNs yielded promising results. Especially, the most efficient results were provided by VGG-16 with an accuracy of 93....
Source: Biocybernetics and Biomedical Engineering - Category: Biomedical Engineering Source Type: research
We present a rare case of a huge Tornwaldt cyst completely obstructing the nasopharyngeal airway. PMID: 31760788 [PubMed - as supplied by publisher]
Source: Ear, Nose and Throat Journal - Category: ENT & OMF Authors: Tags: Ear Nose Throat J Source Type: research
Conclusion: In northern Australia, effective maternal and infant RSV vaccines could substantially reduce RSV bronchiolitis-related hospitalisations, including admissions of Indigenous infants.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Paediatric respiratory epidemiology Source Type: research
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