Human Cartilage Homogenates Influence the Crystallization of Monosodium Urate and Inflammatory Response to Monosodium Urate Crystals: A Potential Link Between Osteoarthritis and Gout

ConclusionIn the presence of elevated urate levels, human cartilage homogenates increase MSU crystal formation and promote the formation of smaller crystals, which have greater inflammatory potential. These processes may contribute to the predilection of osteoarthritic joints to develop gout.

Source: Arthritis and Rheumatology - November 5, 2019 Category: Rheumatology Authors: Ashika Chhana, Bregina Pool, Yicheng Wei, Ally Choi, Ryan Gao, Jacob Munro, Jillian Cornish, Nicola Dalbeth Tags: Original Article Source Type: research