Anti ‐aquaporin‐4 antibody‐positive neuromyelitis optica spectrum disorder associated with central nervous system tuberculosis

ConclusionsAlthough various cases of active pulmonary, renal and abdominal tuberculosis have been documented in association with NMOsd, no mechanism of association has been discovered; interestingly, the seropositive for NMOsd is variable. We theorized that a genetic background in our population might be associated with this uncommon phenotype. If this phenomenon corresponds to an immune dysfunction caused directly by the bacillus, direct tuberculosis infection or a cross ‐reaction is to be determined.
Source: Clinical and Experimental Neuroimmunology - Category: Neurology Authors: Tags: Case Report Source Type: research