Clinical characteristics, diagnosis, treatment, and prognostic factors of pulmonary mucosa ‐associated lymphoid tissue‐derived lymphoma

MALT lymphoma is an indolent disease with favorable treatment outcomes. There was no significant difference in overall survival between patients treated with and without surgical resection, but surgery still plays an important role in the diagnosis and treatment of MALT. AbstractPrimary pulmonary mucosa ‐associated lymphoid tissue‐derived (MALT) lymphoma is a rare disease with a favorable prognosis. However, its clinical characteristics, diagnosis, treatment, and prognoses remain unclear. We retrospectively analyzed 80 patients with pathologically confirmed MALT lymphoma from 2006 to 2018. The clinical characteristics, diagnosis, treatments, and prognoses of all the 80 patients were recorded. Patients were stratified into surgery and biopsy groups, respectively, to evaluate the role of surgery in the diagnosis and treatment of MALT lymphoma. The prognoses were compared between different c linical characteristics and treatments. Pathological diagnoses were confirmed by surgery, bronchoscopy, and percutaneous biopsy. Thirty patients were treated by surgery. While MALT lymphoma was only diagnosed by bronchofiberoscopy or bercutaneous biopsy in four of 18 patients in the surgery group wh o underwent the procedure. Six patients received adjuvant chemotherapy and one patient received involved‐field radiotherapy in surgery group. Thirty‐one patients were treated with chemotherapy alone, one patient was treated with radiotherapy, one patient received only symptomatic and supp...

Source: Cancer Medicine - November 4, 2019 Category: Cancer & Oncology Authors: Lin Wang, Guanzhi Ye, Zhonghe Liu, Lin Shi, Cheng Zhan, Jie Gu, Rongkui Luo, Zongwu Lin, Di Ge, Qun Wang Tags: ORIGINAL RESEARCH Source Type: research