First trimester depression and/or anxiety disorders increase the risk of low birthweight in IVF offspring: a prospective cohort study
Publication date: Available online 11 September 2019Source: Reproductive BioMedicine OnlineAuthor(s): Jingwen Lang, Bingqian Zhang, Yueru Meng, Yanzhi Du, Linlin Cui, Weiping LiAbstractResearch questionAre maternal depression and/or anxiety disorders (MDAD) before and during pregnancy associated with IVF outcomes?DesignA total of 5661 women starting their first IVF cycle between 15 August 2014 and 31 December 2015 were pooled from a prospective cohort of IVF-conceived children. The self-rating depression scale (SDS) and self-rating anxiety scale (SAS) were used to determine MDAD. IVF outcomes were compared between MDAD+ and MDAD– groups.ResultsA total of 10.3% (572) of women had MDAD before IVF (bMDAD). The fertilization rate was lower in the bMDAD+ group (59.41 ± 22.11% versus 61.72 ± 22.18%, Padjust
Conditions: Apnea, Obstructive Sleep; Obesity Intervention: Device: Bioelectrical Impedance Analysis (BIA) Sponsor: Samuel Lunenfeld Research Institute, Mount Sinai Hospital Recruiting
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Publication date: Available online 11 September 2019Source: Reproductive BioMedicine OnlineAuthor(s): Jingwen Lang, Bingqian Zhang, Yueru Meng, Yanzhi Du, Linlin Cui, Weiping LiABSTRACTResearch QuestionAre maternal depression and anxiety disorders (MDAD) before and during pregnancy associated with in vitro fertilization (IVF) outcomes?DesignA total of 5556 women with their first IVF cycle started between August 15th, 2014, and December 31st, 2015 were pooled from a prospective cohort of assisted reproductive technology (ART) children. The self-rating depression scale (SDS) and self-rating anxiety scale (SAS) were used to d...
In this study, a link between mitochondrial changes and infant temperament has also been suggested. Maternal psychosocial stress and lifetime trauma have been associated with decreased mitochondrial DNA copy number in the placenta (115, 116).IndividualityChronic stress links changes in the epigenetic landscape with health conditions (117). Different cell types are characterized by distinct patterns of gene expression due to developmental, environmental, physiological, and pathological reasons (117). Epigenetic mechanisms affect gene function in a dynamic way as a result of different environmental exposures during fetal dev...
ConclusionThe results of the study indicate that diaphragmatic breathing exercises appear to provide positive effects on psychological state and may increase levels of maternal-foetal attachment.
AbstractBackgroundWomen with diabetes experience an increased risk of adverse pregnancy outcomes.AimWe aim to describe and quantify the psychological impact of the diagnosis of diabetes in pregnant women with type 1 diabetes and gestational diabetes mellitus (GDM) compared to each other and to their counterparts without diabetes.DesignThis is a survey-based study with prospective collection of pregnancy outcome data.MethodsA total of 218 pregnant women (50% with diabetes) were administered questionnaires relating to psychological health. Maternal and neonatal characteristics and pregnancy outcomes were collected. Associati...
Conclusion The incidence of severe state anxiety in early pregnancy is more frequent in women with diabetes or hyperglycemia, but their levels of trait anxiety and depression are not affected by glycemic status.