Humans Shipped an Awful Cargo Across the Seas: Cancer

A cancer afflicting mussels originated off the Pacific coast of Canada, but then crossed into other species in Europe and South America.
Source: NYT Health - Category: Consumer Health News Authors: Tags: your-feed-science Tasmanian Devils Mussels Dogs Invasive Species Tumors Animals Biology and Biochemistry Cancer eLife (Journal) Murchison, Elizabeth Canada Chile France Source Type: news

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Source: Medical Care - Category: Health Management Tags: Errata Source Type: research
Abstract Retrospective analysis has already shown correlation between severe Chronic Periodontitis (CP) cases with human papiloma virus (HPV). Hence, we aimed to explore deep-seated infected granulation tissue removed during periodontal flap surgery procedures for residential bacterial species between HPV+ and HVP- CP cases, which may serve as good predisposition marker for oral cancer. All CP-granulation samples showed the prominence of Firmicutes, Proteobacteria, and Bacteroidetes phyla with an abundance of gram negative anaerobes, except Streptococcus. In Beta diversity nonmetric multidimensional scaling plot, ...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Abstract An important harmonization effort was produced by the scientific community to standardize both the preanalytical and interpretative phases of programmed death-ligand 1 (PD-L1) immunohistochemical (IHC) testing in non-small-cell lung cancer (NSCLC). This analysis is crucial for the selection of patients with advanced-stage tumors eligible for treatment with pembrolizumab and potentially with other anti-PD-1/PD-L1 checkpoint inhibitors. This multicentric retrospective study evaluated the reproducibility of PD-L1 testing in the Italian scenario both for closed and open platforms. In the evaluation of the wel...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
[News24Wire] Springbok star Faf de Klerk has pulled the national underpants out again to kick off the "#FafChallenge" - to get men to check their "crown jewels" for signs of testicular cancer.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
[Nation] Kenya is on course in the immunisation of 800,000 girls against cervical cancer, Health Cabinet Secretary Sicily Kariuki has said, and allayed fears about the safety of the vaccine.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Publication date: Available online 12 November 2019Source: Journal of Functional FoodsAuthor(s): Mónica Lara-Márquez, Marisol Báez-Magaña, Cristina Raymundo-Ramos, Paul A. Spagnuolo, Lourdes Macías-Rodríguez, Rafael Salgado-Garciglia, Alejandra Ochoa-Zarzosa, Joel E. López-MezaAbstractColorectal cancer (CRC) is the third most common type of cancer worldwide. Chemotherapy used in CRC patients has severe side effects. As an alternative, the search to identify natural compounds increases the opportunity to select therapeutics. In this work, the cytotoxic effect of a lipid extra...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
CONCLUSIONS Eriocalyxin B induces apoptosis and autophagy involving the Akt/mTOR pathway in prostate cancer cells in vitro. These findings provide evidence for Eriocalyxin B as a potent therapeutic for the treatment of prostate cancer. PMID: 31714902 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Authors: Li W, Cao Z, Liu R, Liu L, Li H, Li X, Chen Y, Lu C, Liu Y Abstract Gold nanoparticles (AuNPs), as a kind of inorganic nanoparticle, have been gradually recognized as one of the most promising nanomaterials, which is attributed to their unique optical, electronic, sensing and biochemical characteristics. Due to such unique characteristics, AuNPs have been widely applied in biomedical fields such as diagnosis, biosensing and drug delivery. Except for their use in cancer treatment alone with their photothermal ablation of solid tumours, when used with anticancer drugs, AuNPs can exert a dual role in treating...
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
Authors: Gan L, Guo M, Si J, Zhang J, Liu Z, Zhao J, Wang F, Yan J, Li H, Zhang H Abstract Radiotherapy (RT) is a common treatment for head and neck cancers, but central nervous system function can be impaired by clinical radiation doses. This experimental study evaluated the protective efficacy of the anti-hyperglycaemic/anti-neoplastic agent phenformin against radiation-induced developmental toxicity in zebrafish embryos. Zebrafish embryos pre-treated with 25 μM phenformin 1 h before x-ray irradiation were compared to irradiation-only embryos for mortality, hatching rate, morphology, spontaneous ...
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
Authors: Liang C, Li N, Cai Z, Liang R, Zheng X, Deng L, Feng L, Guo R, Wei B Abstract At present, cancer is the first cause of death for humans, but early detection and treatment can help improve prognoses and reduce mortality. However, further development of carrier-assistant drug delivery systems (DDSs) is retarded by the aspects such as the low drug-carrying capacity, carrier-induced toxicity and immunogenicity, complex synthesis manipulation. The development of nanoscale drug delivery systems (NDDS) have been rapidly developed to address these issues. In this article, we used PLGA-PEG with good biocompatibilit...
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
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