Circ-SLC7A5, a potential prognostic circulating biomarker for detection of ESCC

Esophageal carcinoma (EC) is one of the most common malignant tumors worldwide, of which, 90% are esophageal squamous cell carcinoma (ESCC) [1]. The incidence of ESCC in China accounts for more than 70% of the world and is characterized by its remarkable geographic distribution and high-risk areas especially in Henan province [2]. Despite the recent advances in treatment, the benefit of all kinds of treatments is not satisfactory and the prognosis of patients with ESCC is still poor with the 5-year overall survival rate ranging from 20% to 30% [3].

Source: Cancer Genetics and Cytogenetics - November 6, 2019 Category: Genetics & Stem Cells Authors: Qian Wang, Han Liu, Zihao Liu, Lili Yang, Jian Zhou, Handong Sun, Xiufeng Cao Source Type: research