MAL adaptor (TIRAP) S180L polymorphism and tuberculosis disease severity among TB patients.
CONCLUSIONS: Although mice experiments showed promising results with more severe disease in C/C and T/T individuals, we did not observe any such association in humans. PMID: 31678649 [PubMed - as supplied by publisher]
Conclusion: Multiplex PCR using MPB 64 and IS6110 primers has a high sensitivity and specificity in diagnosis of FGTB. PMID: 31801325 [PubMed - in process]
ConclusionA high suspicion level for TB, the early diagnosis and the prompt initiation of therapy could increase the survival rates among SOT patients. Overall, renal and lung TRs appear to have a higher predisposition for acquiring TB than other type of recipients. Monitoring of the high-risk recipients, prompt diagnosis, and appropriate treatment are required to manage TB infection among TRs especially in endemic areas.
Conclusions: The results show that intricate TB cases were notified by the local health services. Strategies of surveillance and articulation with these health services seem to contribute to the identification of TB cases among PDL.
We report the first evaluation of clinical specimens with REFtb assays in comparison to the gold standards for tuberculosis diagnosis, culture and smear microscopy. REFtb assays allowed diagnosis of 160 patients from 16 different countries with a sensitivity of 89% for smear-positive, culture-positive samples and 88% for smear-negative, culture-positive samples with a specificity of 82%. The negative predictive value of REFtb for tuberculosis infection is 93%, and the positive predictive value is 79%. Overall, these data point toward the need for larger accuracy studies by third parties using a commercially available REFtb...
Conclusion: social vulnerable and comordid IDUs have high risk for TB. They should be screened annually and have an individualized approach for preventing low treatment outcome.
Conclusion: Pulmonary TB has negative impact on male sexual function. Thus, sexual problems should be in mind during assessment and evaluation of patient with tuberculosis.
Background: Diabetes mellitus (DM) has an influence on many aspects of tuberculosis (TB).Objectives: to correlate the influence of diabetes mellitus on sputum conversion rate and antituberculous drug resistance.Methods: The study comprised 194 pulmonary tuberculosis (PTB) patients divided in two groups, i.e. the group of TB associated with DM and the group of patients affected only by TB. Sputum smear and liquid culture (MGIT 960) examination were performed at TB diagnosis and subsequently at completion of the initial phase as well as during the continuation phase of TB treatment. Drug sensitivity test (DST) was also perfo...
Conclusion: Patient with ABPA frequently received empiric ATT as smear –ve TB in high TB burden country. This results in over diagnosis of TB and unnecessary use of global resource. Moreover dealy in diagnosis leads to long term complications. Awareness regarding ABPA is required in high TB burden countries.
Conclusions: Xpert MTB/RIF using EBUS-TBNA samples is a useful laboratory test with good specificity in the diagnosis of tuberculosis. In high prevalence countries of Tuberculosis, Xpert MTB/RIF can decrease the diagnosis and treatment initiation time when combined with the conventional microscopy and histopathology