Dementia: comorbidities in patients - data briefing

Overall findings from this briefing show that patients with dementia are more likely to have multiple health conditions; 22% with>3 comorbidities and 8% with>4 comorbidities vs 11% and 3%, respectively, in all patient group (same list of health conditions, excluding dementia).
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news

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Source: Clinical Interventions in Aging - Category: Geriatrics Tags: Clinical Interventions in Aging Source Type: research
Publication date: Available online 12 November 2019Source: The Lancet PsychiatryAuthor(s): Laura McWhirter, Craig Ritchie, Jon Stone, Alan CarsonSummaryCognitive symptoms are common, and yet many who seek help for cognitive symptoms neither have, nor go on to develop, dementia. A proportion of these people are likely to have functional cognitive disorders, a subtype of functional neurological disorders, in which cognitive symptoms are present, associated with distress or disability, but caused by functional alterations rather than degenerative brain disease or another structural lesion. In this Review, we have systematical...
Source: The Lancet Psychiatry - Category: Psychiatry Source Type: research
This study was designed to test the hypothesis that nondependent alcohol drinking exacerbates the onset and magnitude of AD-like neural and behavioral pathology. We first evaluated the impact of voluntary 24-h, two-bottle choice home-cage alcohol drinking on the prefrontal cortex and amygdala neuroproteome in C57BL/6J mice and found a striking association between alcohol drinking and AD-like pathology. Bioinformatics identified the AD-associated proteins MAPT (Tau), amyloid beta precursor protein (APP), and presenilin-1 (PSEN-1) as the main modulators of alcohol-sensitive protein networks that included AD-related proteins ...
Source: International Review of Neurobiology - Category: Neuroscience Source Type: research
Publication date: 2019Source: International Review of Neurobiology, Volume 148Author(s): Sara Jo Nixon, Ben LewisAbstractEpidemiological estimates indicate not only an increase in the proportion of older adults, but also an increase in those who continue moderate alcohol consumption. Substantial literatures have attempted to characterize health benefits/risks of moderate drinking lifestyles. Not uncommonly, reports address outcomes in a single outcome, such as cardiovascular function or cognitive decline, rather than providing a broader overview of systems. In this narrative review, retaining focus on neurobiological consi...
Source: International Review of Neurobiology - Category: Neuroscience Source Type: research
Researchers from Columbia University in New York followed 983 people with an average age of 77 over four years. They found the risk of dementia trebled in those who were illiterate.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
(Natural News) Dementia is a collective term for diseases like Alzheimer’s that affect a person’s brain and his ability to think and remember. With over 50 million people having dementia worldwide and 10 million new cases being diagnosed annually, it is one of the fastest growing health conditions globally. Common signs of early-stage dementia are impaired cognitive...
Source: - Category: Consumer Health News Source Type: news
A study of 35 people with and without Alzheimer's disease found that hyperspectral imaging of the retina could aid early diagnosis of the disease.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Alzheimer's / Dementia Source Type: news
Authors: Wang L, Lakin J, Riley C, Korach Z, Frain LN, Zhou L Abstract Despite the increasing prevalence, growing costs, and high mortality of dementia in older adults in the U.S., little is known about the course of these diseases and what care dementia patients receive in their final years of life. Using a large volume of clinical notes of dementia patients over the last two years of life, we conducted automatic topic modeling to capture the trends of various themes mentioned in care provider notes, including patients' physical function status, mental health, falls, nutrition and feeding, infections, hospital car...
Source: AMIA Annual Symposium Proceedings - Category: Bioinformatics Tags: AMIA Annu Symp Proc Source Type: research
WEDNESDAY, Nov. 13, 2019 -- Could illiteracy up your odds for dementia? That's the suggestion of a study that found seniors who couldn't read or write were two to three times more likely to develop dementia than those who could. The finding...
Source: - Daily MedNews - Category: General Medicine Source Type: news
CONCLUSIONS: Brexpiprazole 2 mg/day has the potential to be efficacious, safe, and well tolerated in the treatment of AAD. PMID: 31708380 [PubMed - as supplied by publisher]
Source: The American Journal of Geriatric Psychiatry - Category: Psychiatry Tags: Am J Geriatr Psychiatry Source Type: research
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