Febrile Infection-Related Epilepsy Syndrome Treated Successfully With Anakinra in a 21-Year-Old Woman.

DISCUSSION: Here we report what we believe is the second case of super-refractory status epilepticus due to FIRES responding to anakinra, and the first such case in an adult patient. Anakinra was well tolerated with few side effects. Our results are further evidence for the autoinflammatory nature of FIRES and support the use of anakinra early in the treatment to prevent long-term sequelae. PMID: 31682750 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31682750?dopt=Abstract

Source: WMJ - September 30, 2019 Category: General Medicine Authors: Westbrook C, Subramaniam T, Seagren RM, Tarula E, Co D, Furstenberg-Knauff M, Wallace A, Hsu D, Payne E Tags: WMJ Source Type: research