Inhibition of nociceptive dural input to the trigeminocervical complex through oxytocinergic transmission.

This study provides the first direct evidence that oxytocin, probably by OTR activation at TCC level inhibited dural nociceptive-evoked action potential in this complex. Thus, targeting OTR at TCC could represent a new avenue to treat migraine. PMID: 31678349 [PubMed - as supplied by publisher]
Source: Experimental Neurology - Category: Neurology Authors: Tags: Exp Neurol Source Type: research

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CONCLUSION: This study showed that calcitonin could be helpful analgesic agent in different painful situations. Calcitonin can be considered an eligible treatment for acute pains related to vertebral fractures and a feasible alternative for the treatment of the acute and chronic neuropathic pains where other medications might fail. PMID: 31810524 [PubMed - as supplied by publisher]
Source: Revista Brasileira de Anestesiologia - Category: Anesthesiology Tags: Rev Bras Anestesiol Source Type: research
Source: Journal of Pain Research - Category: Anesthesiology Tags: Journal of Pain Research Source Type: research
Conclusions: Spinal anesthesia with a median or paramedian approach at cesarean section has no effect on the incidence of PDPH, but we believe that there has been a need for further studies with larger or different patient populations.
Source: Nigerian Journal of Clinical Practice - Category: Rural Health Authors: Source Type: research
ConclusionThis study showed that calcitonin could be helpful analgesic agent in different painful situations. Calcitonin can be considered an eligible treatment for acute pains related to vertebral fractures and a feasible alternative for the treatment of the acute and chronic neuropathic pains where other medications might fail.ResumoJustificativa e objetivosA calcitonina é um hormônio polipeptídico que regula o metabolismo do cálcio no organismo. Por muitos anos a calcitonina tem sido usada para manter e melhorar a densidade mineral óssea e reduzir a incidência de fraturas. Muitos ...
Source: Brazilian Journal of Anesthesiology - Category: Anesthesiology Source Type: research
A review of 14 studies found that people with persistent headache or back pain were about twice as likely to also experience the other condition.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Pain / Anesthetics Source Type: news
A review of 14 studies found that people with persistent headache or back pain were about twice as likely to also experience the other condition.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Pain / Anesthetics Source Type: news
Conditions:   Headache Disorders, Secondary;   Post-Dural Puncture Headache;   Migraine Disorders;   Back Pain;   Anesthesia Intervention:   Sponsor:   Stanford University Active, not recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionsIH is an under-recognized cause of seizure following the spinal or cranial surgery, lumbar puncture, or spinal anesthesia. Proposed mechanisms include traction on cortical structures, increased cerebral blood flow, and cortical irritation secondary to subdural hygromas.
Source: Neurocritical Care - Category: Neurology Source Type: research
AbstractPurpose of ReviewThe erector spinae plane block (ESPB), first described in 2016, offers the promise of becoming a safe, less invasive, and technically less demanding alternative to conventional thoracic regional anesthetic techniques including thoracic epidurals and traditional paravertebral blocks. Clinical and cadaveric studies suggest that ESPB acts on the ventral rami of spinal nerves in the paravertebral space via penetration of the intertransverse connection tissues and moreover achieves visceral analgesia via the rami communicantes and sympathetic chain.Recent FindingsThe block has garnered considerable appe...
Source: Current Pain and Headache Reports - Category: Neurology Source Type: research
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