Lung transplant girl has pneumonia
Less than a month after two lung transplant surgeries to save Sarah Murnaghan's life, the 10-year-old has developed pneumonia in her second set of replacement lungs, her mother posted on Monday.
We describe the case of a 67-year old male bilateral lung transplant recipient (LTR) who developed recurrent episodes of multi-drug resistant (MDR) Pseudomonas aeruginosa (PA) pneumonia in the setting of right anastomotic stricture requiring airway stent placement and chronic lung allograft dysfunction. We obtained an emergency Investigational New Drug approval from the US Food and Drug Administration to use sequential bacteriophage combinations (BC) as adjunctive treatment to systemic antibiotics.
The objective of this study was to investigate the epidemiology and the risk factors of post operative pneumonia in recipients beneficing of heart transplantation.
CONCLUSIONS Despite great progress in the management of ARDS, based mostly on advanced mechanical ventilation, early antiviral treatment of pneumonia caused by influenza A (H1N1) and annual vaccinations seem essential in prevention and management of influenza A (H1N1) infection among kidney transplant recipients. PMID: 29599422 [PubMed - in process]
This study analyzed epidemiology and outcome of 175 consecutive...
CONCLUSIONS: We found that mean platelet volume for diagnosis of pneumonia in solid-organ transplant patients was not a promising tool. Considering the difficulties in caring for transplant patients with pulmonary infiltrates, clinical decisions should be based on clinical, laboratory, microbiological, and radiologic findings. PMID: 29528024 [PubMed - in process]
Conclusion: Despite a high percentage of patients who required preoperative intensive care, the transplantation outcomes were acceptable. PMID: 29430425 [PubMed]
Cryptococcus neoformans (wikipedia.org) 2.5 out of 5 stars Cryptococcal meningitis in a daily cannabis smoker without evidence of immunodeficiency. Shapiro BB et al. BMJ Case Rep 2018 Jan 26 [Epub ahead of print] Abstract Can smoking marijuana cause meningitis? The question is not unreasonable. A wide range of pathogenic fungi — including Aspergillus and various Cryptococcus species — have been isolated from dispensary-grade medical marijuana samples. Concern that these pathogens could cause pneumonia or central nervous system infections has focussed on those with immunodeficiency, such...
In this study, we aim to identify early immune predictors to detect allo-LS and find support for activation of the immune system by viral infection.
Conclusions CMV PCR viral load in BAL had a high performance to diagnose CMV pneumonia in lung transplant recipients; plasma CMV viral load did not reliably aid as a diagnostic tool.
S. Basu et al.