Medical groups differ on when to start colon and rectal cancer screening. Here's why

Conflicting recommendations on when and how average-risk adults should get screened for colon and rectal cancer could leave you confused. Now a new guidance statement from the American College of Physicians or ACP aims to help make sense of that discord.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news

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ConclusionsMale gender, diffuse peritonitis, positive lymph nodes, type of surgeon and postoperative anastomotic dehiscence significantly influence recurrence of  colorectal cancer in this series.
Source: Techniques in Coloproctology - Category: Surgery Source Type: research
ConclusionsAn 11-point modified frailty index as measured in NSQIP correlates with readmissions after colorectal resection in patients with colon and rectal cancer.
Source: The American Journal of Surgery - Category: Surgery Source Type: research
Publication date: Available online 11 November 2019Source: Pathology - Research and PracticeAuthor(s): Can Yi, Chao Huang, Huan Wang, Chen Wang, Lijuan Dong, Xiuli Gu, Xianhong Feng, Bifeng ChenAbstractCYP24A1, an essential gene in regulation of vitamin D, has been reported to play an important role in enhancing immune activity and inhibiting tumorigenesis. Previous studies proposed that rs2585428, rs4809960, rs6022999 and rs6068816 in CYP24A1 gene might be greatly associated with cancer risk. To validate the findings, we here investigated the associations of these four polymorphisms and colorectal cancer (CRC) risk in a c...
Source: Pathology Research and Practice - Category: Pathology Source Type: research
This study aims to assess long-term outcomes of emergency versus elective CRC surgery.MethodsSingle-center retrospective cohort study. Patients undergoing emergency or elective CRC surgery from July 2002 to January 2013 were included. Primary outcome was 5-year survival, secondary outcomes were in-hospital mortality and local tumor recurrence.ResultsOverall, 475 patients were included. Median age was 69.0 (IQR 59.0 –77.0) years. A total of 141 patients (30%) were operated for rectal cancer and 334 patients (70%) for colon cancer. Median follow-up was 445 (IQR 67–1409) days. Emergency resection was performed in ...
Source: International Journal of Colorectal Disease - Category: Gastroenterology Source Type: research
We examined the relation of cardiorespiratory fitness to colorectal cancer in 59,191 UK Biobank participants aged 39 –70 years without prevalent cancer at baseline, followed from 2009 to 2014. Submaximal bicycle ergometry was conducted at study entry, and cardiorespiratory fitness was defined as physical work capacity at 75% of the maximum heart rate, standardised to body mass (PWC75%). Multivariable Cox proportional hazards regression was performed to obtain hazard ratios (HR) and corresponding 95% confidence intervals (CI). During a mean follow-up of 4.6  years, 232 participants developed colorectal cance...
Source: European Journal of Epidemiology - Category: Epidemiology Source Type: research
Clinics in Colon and Rectal Surgery DOI: 10.1055/s-0039-1698395Transanal total mesorectal excision (taTME) is the culmination of major developments in rectal cancer management and minimally invasive surgery. This surgical breakthrough holds great promise and excitement for the care of the rectal cancer patient. We would be remiss in discussing taTME to not acknowledge the role of transanal abdominal transanal proctosigmoidectomy, transanal endoluminal microsurgery, laparoscopy, and natural orifice transluminal endoscopic surgery that got us to this modern day explosion of the taTME approach. In this article, we detail and ...
Source: Clinics in Colon and Rectal Surgery - Category: Surgery Authors: Tags: Review Article Source Type: research
Oral antibiotic use is linked to an increased risk of colon cancer, but a reduced risk of rectal cancer, a study in Gut  suggests.
Source: The Pharmaceutical Journal - Category: Drugs & Pharmacology Source Type: research
Conclusion: Correct differential diagnosis between primary and metastatic ovarian tumors is paramount in choosing the best treatment which leads to the best possible outcome. In ovarian metastatic tumors, immunohistochemistry could represent an optimal diagnostic tool.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
ConclusionTotal transanal mesorectal excision has been shown to be a viable method for oncologic resection of locally advanced rectal cancer with curative intent.ResumoContextoA excisão total do mesorreto por via transanal é uma aborgadem crânio-caudal para a realização de ressecção minimamente invasiva do reto e tecidos perirretais em monobloco. É adequada para pacientes com câncer de reto médio e distal confinados ao envelope mesorretal. Aqui relatamos uma série de pacientes submetidos à excisão total do mesorreto por via transanal.M...
Source: Journal of Coloproctology - Category: Gastroenterology Source Type: research
Authors: Nomura M, Takahashi H, Fujii M, Miyoshi N, Haraguchi N, Hata T, Matsuda C, Yamamoto H, Mizushima T, Mori M, Doki Y Abstract The T3 subdivision has been reported to predict prognosis in rectal cancer. However, few studies describe a correlation between T3 subdivision and prognosis in colon cancer. The current study aimed validate the correlation between the invasion distance (ID) beyond the muscularis propria and prognosis in colorectal cancer. The present retrospective study included 148 consecutive patients with pathologically confirmed T3 colorectal cancer, who underwent resection between January 2008 an...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
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