Interhemispheric pathways in agenesis of the corpus callosum and Parkinson ’s disease

Several transcranial magnetic stimulation (TMS) measures of interhemispheric transfers are thought to be mediated mainly by transcallosal pathways [1-4]. Ipsilateral silent period (iSP) is the suppression of motor output by TMS of the ipsilateral primary motor cortex (M1). iSP is absent or delayed in patients with corpus callosum (CC) abnormalities, including agenesis of the corpus callosum (ACC) [1,3]. Interhemispheric inhibition (IHI) is studied with paired-pulse bilateral M1 TMS using short (SIHI) or long (LIHI) interstimulus intervals [2].
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - Category: Neurology Authors: Source Type: research