Over-the-counter painkillers may cut skin cancer risk
Drugs like Advil, Motrin and Aleve could offer protection but also come with some risks of their own
Conclusion: Our preliminary findings support the possibility of an enhanced risk of early onset basal cell carcinomas at the site of cosmetic tattoos.
Conditions: Non-melanoma Skin Cancer; Melanoma; Hypertension Interventions: Drug: Hydrochlorothiazide; Drug: Angiotensin-converting enzyme (ACE) inhibitors Sponsors: Canadian Network for Observational Drug Effect Studies, CNODES; Drug Safety and Effectiveness Network, Canada; Canadian Institutes of Health Research (CIHR) Active, not recruiting
Photochem. Photobiol. Sci., 2020, Advance Article DOI: 10.1039/C9PP00284G, PaperFl ávia Amanda Pedroso de Morais, Renato Sonchini Gonçalves, Bruno Henrique Vilsinski, Danielle Lazarin-Bidóia, Rodolfo Bento Balbinot, Tayana Mazin Tsubone, Kellen Brunaldi, Celso Vatatu Nakamura, Noboru Hioka, Wilker Caetano The Hyp/DPPC formulation photodynamic effect in melanoma B16-F10 cells pointed out its potentiality for PDT against cancer cells. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Contributors : M Georganaki ; M Ramachandran ; S Tuit ; N Nunez ; A Karampatzakis ; G Fotaki ; L van Hooren ; H Huang ; R Lugano ; T Ulas ; A Kaunisto ; E Holland ; P Ellmark ; S M Mangsbo ; J L Schultze ; M Essand ; S Tugues ; A DimbergSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusCD40-stimulating immunotherapy elicits potent anti-tumor responses, which are mainly T-cell dependent. Here, we have investigated how tumor endothelial cells respond to CD40-stimulating immunotherapy by isolating endothelial cells from B16.F10 melanoma in anti-CD40 treated or isotype treated mice followed...
ConclusionsCurrent clinical trials are exploring combination therapy and novel treatment strategies beyond immune checkpoint therapies and vaccine therapy such as CAR T cells. There is also an effort to establish synergy between immunotherapy and current standard of care. Furthermore, recent advances in personalized neoantigen vaccines suggest a shift towards personalized, patient-specific GBM treatment.
ConclusionsB4GALNT4 influences the malignant behavior of ESCC cells.B4GALNT4 expression may serve as a novel prognostic marker, independent of established risk factors, for ESCC patients.
ConclusionIn MBM patients, complications after GKRS are not significantly increased if IT/TT treatment is performed at the time of or after radiosurgery. Further, a clear benefit in distant control and survival is seen in MBM patients treated with GKRS and checkpoint inhibitors. Thus, concomitant treatment of MBM with GKRS and IT/TT seems to be a safe and powerful treatment option although further prospective studies should be conducted.
Tongue cancer is often associated with pain and perineural invasion. The purpose of this study was to determine the association between tongue pain and otalgia and the microscopic identification of perineural invasion in patients with squamous cell carcinoma of the tongue.
Treatment of keratinocytic carcinomas requires an assessment of the extent of tumor spread. Visual delineation of tumor margins is error-prone, due to the limited contrast between cancerous and normal skin. In this contribution we introduce spectrally-encoded optical polarization imaging and evaluate its performance for preoperative demarcation of keratinocytic carcinomas. Subjects with basal or squamous cell carcinoma, scheduled for Mohs surgery, were enrolled. The surgeon outlined the clinical boundary of each lesion preoperatively.
Authors: Vatamanesku I, Parasca SV, Parasca OM, Vaida FA, Mehedinţi MC, Grosu F, Ciurea ME Abstract Basal cell carcinoma (BCC) is the most frequent skin cancer and its location in the nasal pyramid poses treatment problems. The main issue is how large the resection margins should be. The article presents a retrospective study on patients with BCCs of the nose. Thirty-seven patients were included and the correlations between incomplete resections and tumor dimensions, resection margins or histological sub-type were investigated. Of the 37 patients, only five had tumor-positive excision margins, but no correlation w...