P2X7 receptor knockout mice display less aggressive biting behaviour correlating with increased brain activation in the piriform cortex

This study suggests that the P2X7 receptor might serve as a novel target for serenic or anti-OCD therapeutics.Graphical abstract
Source: Neuroscience Letters - Category: Neuroscience Source Type: research

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ConclusionsRumination is known to be associated with poor prognosis in mental health. This study suggests that rumination is a maladaptive coping style associated not only with worry, distress and illness severity, but also with socioeconomic status. Also, rumination demonstrated a specific association with panic disorder.
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
This article is intended to provide an overview of the literature regarding mental disorders associated with polycystic ovary syndrome and to present own research on depression and sexual dysfunction in this group. PMID: 31760419 [PubMed - in process]
Source: Psychiatria Polska - Category: Psychiatry Tags: Psychiatr Pol Source Type: research
Authors: Beszłej JA, Wieczorek T, Kobyłko A, Piotrowski P, Siwicki D, Weiser A, Fila-Witecka K, Rymaszewska J, Tabakow P Abstract Deep brain stimulation (DBS) is a treatment method that is currently getting more and more attention from psychiatrists. It has proven to be efficacious and safe in the treatment of neurological disorders, mainly Parkinson's disease (PD), dystonia and essential tremor. DBS has very often contributed to successful treatment in cases that had proved resistant to all other methods of treatment. Nowadays treatment-resistant obsessive-compulsive disorder (OCD) is the main psychiatric indica...
Source: Psychiatria Polska - Category: Psychiatry Tags: Psychiatr Pol Source Type: research
Conclusions: In>8 years of observation, most participants experienced a robust and sustained antidepressant response to SCC DBS. News in Context: Ethical issues raised around deep brain stimulation (DBS) research Closing the Circuit: Helen Mayberg’s research could revolutionize depression treatment Expo Day: Neuroenginnering, BPI, Arrowsmith Program &ARPF from SharpBrains
Source: SharpBrains - Category: Neuroscience Authors: Tags: Cognitive Neuroscience Health & Wellness Technology antidepressant area-25 brain pacemaker brain stimulation DBS deep-brain-stimulation depression Helen-Mayberg neurosurgical treatment Source Type: blogs
Are you always in control and always perfectly put together? Are you professionally successful, a great friend, and always showing a happy face to the world?  But what about on the inside? Is there something in the background or in the past that you don’t talk about?  Do you feel disconnected, like no one knows the “real” you? Deep down do you just know something is wrong? Well, you might have “perfectly hidden depression.” Today Gabe speaks with Dr. Margaret Rutherford who has done extensive work on the relationship between perfectionism and depression.  Dr. Rutherford tells u...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Brain and Behavior Depression General Happiness Interview LifeHelper Mental Health and Wellness Perfectionism Personality Podcast Psychiatry Psychology Research Self-Esteem Self-Help The Psych Central Show Trauma Source Type: blogs
Each year, the first full week in October has been designated as MENTAL ILLNESS AWARENESS WEEK to raise awareness, educate the public, fight stigma and help support children and adults living with a mental health condition. This year, the dates are October 6th through the 9th.Here Are Some Statistics19.1% of U.S.adults experienced mental illness in 2018 (47.6 million people). This represents 1 in 5 adults.4.6%of U.S. adults experienced serious mental illness in 2018 (11.4 million people). This represents 1 in 25 adults.16.5%of U.S. youth aged 6-17 experienced a mental health disorder in 2016 (7.7 million people)3.7% o...
Source: Dr. Deborah Serani - Category: Psychiatry & Psychology Tags: awareness campaigns mental health Source Type: blogs
Each year, the first full week in October has been designated as MENTAL ILLNESS AWARENESS WEEK to raise awareness, educate the public, fight stigma and help support children and adults living with a mental health condition. This year, the dates are October 6th through the 9th.Here are some Statistics19.1% of U.S. adults experienced mental illness in 2018 (47.6 million people). This represents 1 in 5 adults.4.6% of U.S. adults experienced serious mental illness in 2018 (11.4 million people). This represents 1 in 25 adults.16.5% of U.S. youth aged 6-17 experienced a mental health disorder in 2016 (7.7 mil...
Source: Dr. Deborah Serani - Category: Psychiatry & Psychology Tags: awareness campaigns mental health Source Type: blogs
Neuropsychiatric disorders, such as depression, bipolar, schizophrenia, obsessive-compulsive disorder, and neuropsychiatric disorders such as autism spectrum disorder, are associated with significant illness burden. Accumulating evidence supports an association between neuropsychiatric illnesses and inflammatory processes. Consequently, potent anti-inflammatory agents, such as the cyclooxygenase-2 inhibitors, represent a novel avenue to prevention and treatment of neuropsychiatric illness. In this paper, we first review the role of inflammation in psychiatric pathophysiology including inflammatory cytokines’ influenc...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Conclusions and discussionOur study showed significant associations between migraine headache and psychiatric disorders, as well as with role functioning and disability. The findings of our study emphasise the need for screening for psychiatric comorbidity among those with migraine and the development of appropriate interventions for this group.
Source: Social Psychiatry and Psychiatric Epidemiology - Category: Psychiatry Source Type: research
Publication date: Available online 22 August 2019Source: The Lancet PsychiatryAuthor(s): Meng-Chuan Lai, Caroline Kassee, Richard Besney, Sarah Bonato, Laura Hull, William Mandy, Peter Szatmari, Stephanie H AmeisSummaryBackgroundCo-occurring mental health or psychiatric conditions are common in autism, impairing quality of life. Reported prevalences of co-occurring mental health or psychiatric conditions in people with autism range widely. Improved prevalence estimates and identification of moderators are needed to enhance recognition and care, and to guide future research.MethodsIn this systematic review and meta-analysis...
Source: The Lancet Psychiatry - Category: Psychiatry Source Type: research
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