Correlation of bioimpedance changes after compressive loading of murine tissues in vivo
Objective : Rises in the incidence of pressure ulcers are increasingly prevalent in an aging
population. Pressure ulcers are painful, are associated with increased morbidity and mortality,
increase the risk for secondary infections and inpatient stay, and adds $26.8 billion annually to
the healthcare costs of the USA. Evidence suggests that a change in the bioimpedance of living
tissue in response to continuous local contact pressure can be a useful indicator for the onset of
pressure injuries. Approach : Thirty-five Sprague Dawley rats were subjected to various skin
pressures for differing periods of time via a surgically inserted steel disk and an externally
applied magnet. Contact pressure and bioimpedance were measured and correlated with tissue loading
intensity and compared to clinical ulcer grading. Main results : Moderate relationships between
bioimpedance changes and tissue loading intensity were found. Stronger correlations were found by
utilizing a ...
Source: Physiological Measurement - Category: Physiology Authors: Joshua R Harvey, Devdip Sen, Angel Baez, Kelli Hickle, Heather Tessier, Robert Slamin, Raymond Dunn, John McNeill and Yitzhak Mendelson Source Type: research