A454 Safety and effectiveness of single-stage conversion of adjustable gastric band to laparoscopic sleeve gastrectomy

The laparoscopic adjustable gastric band (AGB) is associated with poor long-term weight loss and frequent untoward outcomes. Increasingly, patients are referred for revisional bariatric surgery, wherein a previously-placed adjustable gastric band is removed in favor of laparoscopic Roux-en-Y gastric bypass or sleeve gastrectomy (SG). Recently, data have emerged that argue for the safety of a 1-stage approach to these maneuvers, which offers potential benefits over a 2-stage approach including fewer instances of general anesthesia, fewer total abdominal procedures, and fewer interruptions in patients ’ lives.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research

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ConclusionsOur study provides fundamental insights on the molecular mechanisms underlying POMC neuron malprogramming in obesogenic contexts.Graphical abstract
Source: Molecular Metabolism - Category: Endocrinology Source Type: research
Authors: Bartelt A, Widenmaier SB Abstract The proper production, degradation, folding and activity of proteins, proteostasis, is essential for any cellular function. From single cell organisms to humans, selective pressures have led to the evolution of adaptive programs that ensure proteins are properly produced and disposed of when necessary. Environmental factors such as temperature, nutrient availability, pathogens as well as predators have greatly influenced the development of mechanisms such the unfolded protein response, endoplasmic reticulum-associated protein degradation and autophagy, working together in ...
Source: Biological Chemistry - Category: Chemistry Tags: Biol Chem Source Type: research
Publication date: Available online 14 February 2020Source: Anaesthesia Critical Care &Pain MedicineAuthor(s): Audrey De Jong, Amélie Rollé, François-Régis Souche, Olfa Yengui, Daniel Verzilli, Gérald Chanques, David Nocca, Emmanuel Futier, Samir JaberAbstractThe obese patient is at risk of perioperative complications including difficult airway access (intubation, difficult or impossible ventilation), and postextubation acute respiratory failure due to the formation of atelectases or to airway obstruction. The association of obstructive sleep apnoea syndrome (OSA) with obesity is very ...
Source: Anaesthesia, Critical Care and Pain Medicine - Category: Anesthesiology Source Type: research
Publication date: Available online 14 February 2020Source: Anaesthesia Critical Care &Pain MedicineAuthor(s): Maha MA Mostafa, Ahmed M Hasanin, Fatema Alhamade, Bassant Abdelhamid, Ahmed G Safina, Sahar M Kasem, Osama Hosny, Mohamed Mahmoud, Eman Fouad, Ashraf Rady, Sarah M Amin
Source: Anaesthesia, Critical Care and Pain Medicine - Category: Anesthesiology Source Type: research
CONCLUSION: No higher prevalence of Mets among individuals with SO when compared to those with obesity only, nor a significant association between SO and higher risk of Mets was found. PMID: 32056530 [PubMed - as supplied by publisher]
Source: Current Cardiology Reviews - Category: Cardiology Tags: Curr Cardiol Rev Source Type: research
(Natural News) Cocoa (Theobroma cacao) is the main ingredient of chocolate, one of the most popular foods on the planet. The seeds of cocoa, also known as cocoa beans, are the only parts used for the production of chocolate. It is estimated that about nine tons of fresh byproducts — which end up as waste — are generated for each...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
AbstractBackground and aims—Āomparative animal study of effectiveness of intermittent administration of lyophilized single-, three- and alive multistrain probiotic in short courses on insulin resistance (IR) in rats with experimental obesity.Methods70 rats were divided into 7 groups (n = 10 in each). Rats of group I were left intact. Newborn rats in groups II-VII were administered monosodium glutamate (MSG) (4 mg/g) by injection. Rats in group II (MSG-obesity group) were left untreated. The rats in groups III-V received lyophilized mono-probioticsB.animalis VKL,B.animalis VKB,L.casei IMVB-7280 respective...
Source: Journal of Diabetes and Metabolic Disorders - Category: Endocrinology Source Type: research
In conclusion, the approach of knowledge visualizations could inform coordinated multi-level decision making for improving food accessibility and reducing chronic diseases in locations defined by patterns of food access measures.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
ConclusionsGreater discordance between surgeon self-reported and actual perioperative VTE chemoprophylaxis is associated with significantly increased risk of VTE. Further understanding of the system characteristics associated with these practices may yield insights into how best to improve appropriate VTE chemoprophylaxis.
Source: Obesity Surgery - Category: Surgery Source Type: research
ConclusionsAlthough PCOS is associated with increased serum levels of AMH, protein expression of AMH and its receptor in the endometrium was not different to controls, and moreover not affected by lifestyle modification. Endometrial AMH-R immunostaining increased significantly during the menstrual cycle in both women with PCOS and controls. Our results imply that circulating AMH is not affecting expression of AMH and its receptor in the endometrium.The clinical trial registry numberID ISRCTN18400086.
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
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