Impact of sublingual nitroglycerin dosage on FFR CT assessment and coronary luminal volume –to–myocardial mass ratio

ConclusionsUse of 0.8  mg versus 0.4 mg of NTG in routine clinical CCTAs significantly increased coronary volume determined from FFRCT analysis but did not alter FFRCT or V/M. Further evaluation of repeat CCTAs in a more contemporaneous fashion using varied nitrate doses and disease severity is needed.Key Points•Fractional flow reserve from computed tomography (FFRCT)is a noninvasive method for evaluating the coronary arteries and relies on nitroglycerin (NTG)to induce coronary vasodilation,but the impact of different NTG dosages is unknown.•Retrospective analysis evaluated use of different NTG doses on FFRCT.•Increased NTG dose increased coronary luminal volume on FFRCTanalysis,but did not change FFRCTvalues.
Source: European Radiology - Category: Radiology Source Type: research