How one county scrambled to keep America measles-free
In Rockland County, New York, a wooded suburb 30 miles north of Manhattan, a teenage boy lay in a room in an empty wing of a health clinic, in a fetal position, coughing.
Rubella, sometimes known as German measles, is an infectious disease caused by the rubella virus, generally involving a mild febrile disease accompanied by rash and lymphadenopathy (Menser et al., 1978; Lambert et al., 2015). While rubella is mostly self-limiting and is asymptomatic for 25% –50% of infections, pregnant women infected in the first trimester can suffer a variety of complications, including miscarriage, stillbirth, and congenital rubella syndrome (CRS) (Panagiotopoulos et al., 1999; Lambert et al., 2015).
Many nations lack access to affordable testing. Now 120m antigen tests will help tackle this dangerous inequalityCoronavirus – latest updatesSee all our coronavirus coverageThe principles of managing infectious disease outbreaks, whether of measles, tuberculosis or Covid-19, are similar. You identify who has been infected by testing for the disease, discover where they acquired the infection and who may have also been infected through contact tracing, and stop the spread by asking those affected to isolate. People who become infected are treated with therapies that modify the course of the disease.It sounds simple, d...
This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/). PMID: 32991819 [PubMed - as supplied by publisher]
PMID: 32970662 [PubMed - in process]
This report discusses a patient aged 72 years who contracted measles following a trip to Asia.
We report a child homozygous for a genomic deletion of the entire coding sequence and part of the 3’U TR of the last exon of IFNAR1, who died from HSE at the age of two years. An older cousin died following vaccination against measles, mumps and rubella at 12 months of age, and another 17-year-old cousin homozygous for the same variant has had other viral illnesses. The encoded IFNAR1 protein is exp ressed on the cell surface but is truncated and cannot interact with the tyrosine kinase TYK2. The patient’s fibroblasts and EBV-B cells did not respond to IFN-α2b or IFN-β, in terms of STAT1, STAT2 and S...
This study included 358 nurses. 77.7% (217) had a protective measles-specific IgG antibodies level. Protection rate was higher among workers aging 40 years (82.6% vs 68.7%; p
Measles (rubeola) is a highly contagious infectious disease with significant morbidity/mortality. Measles-Mumps-Rubella (MMR) is a live-attenuated vaccine used in the United States (US) to prevent measles. This retrospective longitudinal cohort study evaluated childhood MMR vaccination and the risk of a seizure episode and seizure disorder.