Mom: 10-year-old lung transplant recipient has aspiration pneumonia
Girl has sucked up fluid from stomach into right lung, causing acid burn; Another setback for girl who has had two lung transplants
Acute respiratory distress syndrome (ARDS) is a complication of burn injury that affects approximately 40% of mechanically ventilated patients . Lung injury in burn trauma can be attributed to smoke inhalation, fluid resuscitation, ventilator acquired pneumonia, or inflammation secondary to the burn injury itself. Pulmonary failure is a major determinant of both morbidity and mortality in burn patients . Mortality rates associated with ARDS have been reported at 40% without any additional comorbidities such as burn wounds or multi-organ failure [3,4].
Purpose of review The purpose of this review is to provide an overview of the immune response to major surgery, and the ways in which it may be modulated to improve postoperative outcomes. Recent findings Data from patients who have undergone a variety of tissue injuries (surgery, burns, sepsis, trauma) have shown the presence of a conserved ‘genomic storm’ that alters the leukocyte transcriptome, with upregulation of the innate immune response and concomitant downregulation of the adaptive immune response. The innate and adaptive immune systems are often regarded largely distinct. However, more recent evi...
ConclusionsThese findings suggest that outcome disparities exist in burn-injured patients in multiple minority groups.
ConclusionsRecurrent bacteremia increases mortality in military burn casualties. Additional research is needed to address and mitigate the underlying causes, thereby improving survival.
Conclusions: Within a diverse cohort having less common presentations of ARDS, there was apparent variability in the distribution of CRS, VD/VT compared to differences oxygenation dysfunction. Elevated pulmonary dead space still identified patients with higher mortality, as is the case with more common causes of ARDS. PMID: 30233877 [PubMed]
It ’s 1970 and 10-month-old Maurice Elias lay in a hospital bed in the pediatric intensive care unit dangerously malnourished, at just 14 pounds, and with a severe infection in his mouth. The antibiotics that doctors at UCLA had been using to treat Maurice, who had been born without a functional immu ne system, were no longer working.The only way Maurice was going to survive was a bone marrow transplant.“If we couldn't find a way to give Maurice a working immune system, he was going to die. And the only way to do so was with a risky transplant that could be fatal, too,” said Dr. Richard Stiehm, the UCLA d...
Publication date: Available online 10 August 2018Source: BurnsAuthor(s): Reinhard Dolp, Sarah Rehou, Matthew R. McCann, Marc G. JeschkeAbstractObjectivesBurn patients have a highly variable length-of-stay (LOS) due to the complexity of the injury itself. The LOS for burn patients is estimated as one day per percent total body surface area (TBSA) burn. To focus care expectation and prognosis we aimed to identify key factors that contribute to prolonged LOS.MethodsThis was a retrospective cohort-study (2006-2016) in an adult burn-centre that included patients with ≥10% TBSA burn. Patients were stratified into expected-LOS (
Publication date: Available online 9 August 2018Source: Journal de Mycologie MédicaleAuthor(s): M. Khatami, N. Zafarnia, M. Heydarpoor Bami, I. Sharifi, H. SinghAbstractWith increase in isolation of multi and extensive drug resistance hospital pathogens (MDR, XDR) in burn centers of many hospitals in the world, attempt to use nanomaterials for treatment of burn-infected patients is the focus of researches all around the world. In the present investigation silver nanospheres (Ag NSs) has been synthesized by chicory seed exudates (CSE). The various parameters influencing the mechanism of Ag NSs synthesis including tem...
ConclusionThe study group who received complete ventilator bundle practices has got higher weaning scores and shorter duration of the connection to mechanical ventilator than the control group.Relevance to clinical practiceimplementation of complete ventilator bundle elements together among mechanically ventilated patients by the trained nurses could be effective in accelerating the safe weaning of patients and decreasing the duration of the connection to mechanical ventilation.