Using velocity-pressure loops in the operating room: a new approach of arterial mechanics for cardiac afterload monitoring under general anesthesia.

Using velocity-pressure loops in the operating room: a new approach of arterial mechanics for cardiac afterload monitoring under general anesthesia. Am J Physiol Heart Circ Physiol. 2019 Nov 01;: Authors: Hong A, Joachim J, Buxin C, Levé C, Le Gall A, Millasseau S, Mateo J, Civelli V, Serrano J, Mebazaa A, Gayat E, Vallée F Abstract Cardiac afterload is usually assessed in the ascending aorta and can be defined by the association of peripheral vascular resistance (PVR), total arterial compliance (Ctot) and aortic wave reflection (WR). We recently proposed the global afterload angle (GALA) and beta angle derived from the aortic velocity-pressure loop (VP loop) as continuous cardiac afterload monitoring in the descending thoracic aorta. The aim of this study was: (1) to describe the arterial mechanic properties by studying the velocity-pressure relations according to cardiovascular risk (Lo-risk and Hi-risk patients) in the ascending and descending thoracic aorta, and (2) to analyze the association between the VP loop (GALA and beta angle) and cardiac afterload parameters (PVR, Ctot and WR). PVR, Ctot, WR and VP loop parameters were measured in the ascending and descending thoracic aorta in 50 anesthetized patients. At each aortic level, the mean arterial pressure (MAP), cardiac output (CO) and PVR were similar between Lo-risk and Hi-risk patients. In contrast, Ctot, WR, GALA and beta angle were strongly influenced by cardiovascular ...
Source: American Journal of Physiology. Heart and Circulatory Physiology - Category: Physiology Authors: Tags: Am J Physiol Heart Circ Physiol Source Type: research