Holistic primary health care for Aboriginal and Torres Strait Islander prisoners: exploring the role of Aboriginal Community Controlled Health Organisations.

CONCLUSION: A holistic model of care underpinned by a reliable funding model (including access to certain Medicare items) and consistent access to prisoners could strengthen ACCHOs' role in primary health care delivery to people inside or leaving prison. Implications for public health: ACCHOs have an important role to play in the delivery of primary health care to prisoners. Existing models of care for prisoners should be examined to explore how this can occur. PMID: 31667912 [PubMed - as supplied by publisher]
Source: Australian and New Zealand Journal of Public Health - Category: International Medicine & Public Health Authors: Tags: Aust N Z J Public Health Source Type: research

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Publication date: Available online 22 February 2020Source: NeuroImageAuthor(s): Ima Trempler, Paul-Christian Bürkner, Nadiya El-Sourani, Ellen Binder, Paul Reker, Gereon R. Fink, Ricarda I. SchubotzAbstractThe brain's sensitivity to and accentuation of unpredicted over predicted sensory signals plays a fundamental role in learning. According to recent theoretical models of the predictive coding framework, dopamine is responsible for balancing the interplay between bottom-up input and top-down predictions by controlling the precision of surprise signals that guide learning.Using functional MRI, we investigated whether ...
Source: NeuroImage - Category: Neuroscience Source Type: research
Publication date: Available online 21 February 2020Source: NeuroImage: ClinicalAuthor(s): Lennard I. Boon, Arjan Hillebrand, Wouter V. Potters, Rob M.A. de Bie, Naomi Prent, Maarten Bot, P. Richard Schuurman, Cornelis J. Stam, Anne-Fleur van Rootselaar, Henk W. BerendseAbstractDeep brain stimulation (DBS) of the subthalamic nucleus (STN) is an established symptomatic treatment in Parkinson's disease, yet its mechanism of action is not fully understood. Locally in the STN, stimulation lowers beta band power, in parallel with symptom relief. Therefore, beta band oscillations are sometimes referred to as “anti-kinetic&r...
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Patients with Parkinson's disease (PD) face unique challenges when admitted to the hospital. The nature of the disease, complexity of the pharmacotherapeutic home regimens, and the medication-related policies of institutionalized care all contribute to the challenges patients and providers face. In addition, medication errors are common in this population. Incorrectly ordered or omitted home medications or delayed administration can have significant negative consequences including worsening of PD symptoms, dopamine agonist withdrawal syndrome, or malignant or hyperpyrexia syndrome. Also, this patient population may commonl...
Source: Critical Care Nursing Quarterly - Category: Nursing Tags: Original Articles Source Type: research
Medicinal cannabinoid use continues to evolve across the United States, although legitimate federal recognition for medicinal purpose is lacking. Variability exists across states within the United States with respect to legislation, and health care institutions encounter challenges when patients present with a history of medicinal cannabinoid use. Emerging evidence in the field of neurosciences suggests a role of cannabinoids for neurologic medical conditions such as Parkinson disease, multiple sclerosis, and epilepsy. We aim to provide an overview of cannabinoids including a historical perspective, pharmacology, applicati...
Source: Critical Care Nursing Quarterly - Category: Nursing Tags: Original Articles Source Type: research
This study describes the novel strategy for the robust generation of homogeneous MOs using specific combination of dual SMAD inhibitors andin vitro WNT gradient. DAC3.0 MOs generated by our optimized protocol within vivo‐like cellular composition are as structurally and functionally mature as the developing midbrain. DAC3.0 MOs with functional glial cells including astrocytes facilitate MPTP‐basedin vitro disease modeling of PD, suggesting its potential usefulness for an advanced patient ‐specific platform forin vitro disease modeling as well as for drug screening for PD. AbstractRecent studies have demonstrated the ...
Source: Stem Cells - Category: Stem Cells Authors: Tags: Embryonic Stem Cells/Induced Pluripotent Stem Cells Source Type: research
Surgery in Parkinson disease is effective for a select group of patients when optimal medical management is not sufficient. Functional neurosurgery can be used as either a salvage therapy in patients with disabling symptoms or to maintain quality of life and independence before progression to severe disability in high-functioning patients. With recent technological advancements in imaging and targeting as well as novel neuromodulation paradigms, there are numerous options for targeted brain lesions and deep brain stimulation. Surgical decision making and postoperative management in Parkinson disease therefore often require...
Source: Neurologic Clinics - Category: Neurology Authors: Source Type: research
Publication date: Available online 20 February 2020Source: MethodsXAuthor(s): Luis O. Soto-Rojas, Cecilia Bañuelos, Linda Garces-Ramirez, Claudia Luna-Herrera, Yazmin M. Flores-Martínez, Guadalupe Soto-Rodríguez, Bismark Gatica-García, Francisco E. López-Salas, José Ayala-Dávila, María E. Gutiérrez-Castillo, América Padilla-Viveros, Fidel de la Cruz-López, Irma A. Martínez-Davila, Daniel Martinez-FongAbstractAn animal model, suitable for resembling Parkinson's disease (PD) progress, should show both, motor and non-motor alterations. However...
Source: MethodsX - Category: Science Source Type: research
Publication date: Available online 21 February 2020Source: Neurochemistry InternationalAuthor(s): Ansab Akhtar, Sangeeta Pilkhwal SahAbstractAlzheimer's disease (AD) is one of the most common neurodegenerative diseases. Its major pathological hallmarks, neurofibrillary tangles (NFT), and amyloid-β plaques can result from dysfunctional insulin signaling. Insulin is an important growth factor that regulates cell growth, energy utilization, mitochondrial function, autophagy, oxidative stress, synaptic plasticity, and cognitive function. Insulin and its downstream signaling molecules are located majorly in the regions of ...
Source: Neurochemistry International - Category: Neuroscience Source Type: research
PARKINSON'S DISEASE gets progressively worse over time but picking up the condition early on can help those affected to manage their symptoms and maintain quality of life for as long as possible. Finding ways to identify the condition in the early stages is therefore a main research priority, and a new study has developed a pioneering approach to early diagnosis.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
We present the case of a woman with DBS as a treatment for PD, safely treated with ECT for a psychotic depression. Depression severity and motor changes were evaluated on a weekly basis using the Montgomery-Åsberg Depression Rating Scale and the Unified Parkinson's Disease Rating Scale. During the course of ECT, the Montgomery-Åsberg Depression Rating Scale score declined from 34 to 13, and the Unified Parkinson's Disease Rating Scale motor score from 44 to 12 with positive impact on rigidity. Considering the positive impact of ECT on the motor function in our patient, new research should look into ECT as an au...
Source: The Journal of ECT - Category: Psychiatry Tags: Case Reports Source Type: research
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