Kinetics of viral RNA, immunoglobulin-M & G antibodies in Kyasanur forest disease.

This study demonstrated the presence of KFD viral RNA till 18th POD, IgM antibodies till 122nd POD and IgG till the last sample collected. Based on our study an algorithm was recommended for accurate laboratory diagnosis of KFDV infection. A sample collected between 1 and 3 POD can be tested using KFDV real-time reverse transcriptase polymerase chain reaction (RT-PCR); between 4 and 24 POD, the combination of real-time RT-PCR and anti-KFDV IgM enzyme-linked immunosorbent assay (ELISA) tests can be used; between POD 25 and 132, anti-KFDV IgM and IgG ELISA are recommended. PMID: 31670274 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31670274?dopt=Abstract

Source: Indian J Med Res - July 31, 2019 Category: Research Authors: Yadav PD, Gurav YK, Shete AM, Jain R, Nyayanit DA, Pardeshi PG, Viswanathan R, Chiplunkar TR, Awate P, Majumdar TP, Sahay RR, Mourya DT Tags: Indian J Med Res Source Type: research