Prevalence and Genotypes Distribution of HR-HPV among Chinese Women in Sichuan Province.

This study aimed to determine HR-HPV prevalence and genotypes distribution among Chinese women living in Sichuan province. A total of 3089 women were recruited from the Third people's，Hospital of Chengdu in Sichuan province. HR-HPV genotyping were assessed by real-time quantitative PCR. Up to 720 cases (23.3%) were HR-HPV positive. 81.1% (584/720) were detected for a single HR-HPV genotype and 18.9% (136/720) for multiple genotypes. The most frequently detected HPV genotype was HPV52, followed by HPV58, HPV16, and HPV51. Age subgroup analysis showed two peaks for the frequencies of HPV infections, one for the group of women under 29 years old, and the other group over 50 years old. Among the women for whom cytology results were available, HPV16 was the most common detected genotype among women affected by HSIL (32.5%) and SCC, followed by HPV58, HPV33 and HPV52.This is one of the largest studies to demonstrate HPV prevalence and genotypes distribution among Chinese women in Sichuan. The prevalence and genotype distribution of HR-HPV was unique with higher frequencies of HPV52 and HPV58. PMID: 31666495 [PubMed - as supplied by publisher]
Source: Japanese Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Jpn J Infect Dis Source Type: research