Energy Trade-offs in Host Defense: Immunology Meets Physiology.

Energy Trade-offs in Host Defense: Immunology Meets Physiology.
Trends Endocrinol Metab. 2019 Oct 25;:
Authors: Steiner AA, Romanovsky AA
Abstract
Host defense relies not only on microbicidal mechanisms (resistance), but also on management of collateral damage (tolerance). Here, we discuss how this immunology concept converges with a physiology-born theory on the dichotomy of thermometabolic responses in infection (fever versus hypothermia), yielding a model of immunity that transcends discipline barriers.
PMID: 31668960 [PubMed - as supplied by publisher]

Source: Trends in Endocrinology and Metabolism: TEM - October 24, 2019 Category: Endocrinology Authors: Steiner AA, Romanovsky AA Tags: Trends Endocrinol Metab Source Type: research