Comparison of Static and Dynamic 18F-FDG PET/CT for Quantification of Pulmonary Inflammation in Acute Lung Injury

Conclusion: The Ki–SURstat correlations were considerably stronger than the Ki–SUV correlations. The good Ki–SURstat correlations suggest that static 18F-FDG PET/CT and SURstat analysis provides an alternative to dynamic 18F-FDG PET/CT and Patlak analysis, allowing the assessment of inflammation of whole lungs, repeated measurements within the period of 18F-FDG decay, and faster data acquisition.
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Basic Source Type: research

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Conclusions: Substantial agreement exists among experts regarding many strong recommendations for the best early management of severe abdominal trauma.
Source: Anaesthesia, Critical Care and Pain Medicine - Category: Anesthesiology Source Type: research
At the RSNA 2019 conference in Chicago, Canon Medical showed off its brand new Aquilion ONE / PRISM Edition spectral CT scanner, a system that takes advantage of artificial intelligence technologies. The device relies on Canon’s Advanced int...
Source: Medgadget - Category: Medical Devices Authors: Tags: Anesthesiology Cardiology Critical Care Diagnostics Emergency Medicine Neurology Ob/Gyn Oncology Radiology Source Type: blogs
ConclusionPatients with an increased femoral anteversion angle (>  30°) had inferior postoperative clinical outcomes, including greater patellar laxity, a higher rate of residual J-sign and lower patient-reported outcomes after medial patellofemoral ligament reconstruction and combined tibial tubercle osteotomy for the treatment of recurrent patellar instabilit y.Level of evidenceIII, retrospective cohort study.
Source: Knee Surgery, Sports Traumatology, Arthroscopy - Category: Orthopaedics Source Type: research
Introduction - Fusion imaging, which provides image guidance by overlaying preoperative 3D vessel anatomy from the preoperative CT scans onto live fluoroscopic images, is being used in endovascular repair to decrease radiation and contrast dose (1). Cloud-based image tracking software has been shown to be more accurate than hardware-tracking systems in these procedures(2). The aim of this study is to determine the accuracy of this technique when patient movement is greatest, for procedures done under local or regional anaesthesia.
Source: European Journal of Vascular and Endovascular Surgery - Category: Surgery Authors: Source Type: research
We present a case series of three patients presenting to our unit with forehead lacerations following a fall. All cases had normal GCS, no obvious neurology and listed for wound closure under general anaesthesia.
Source: The British Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Authors: Tags: P214 Source Type: research
The aim of this study was to correlate the exam under anesthesia (EUA) using the load and shift exam with CT scan or MRI measurements of the glenoid track in order to provide another tool for confirming the best surgical management of bipolar lesions.
Source: Arthroscopy - Journal of Arthroscopic and Related Surgery - Category: Surgery Authors: Source Type: research
ConclusionsThe route of fluid administration has a minor influence on the changes in circulating and splenic leukocytes post-burn in the acute phase. Further research is needed to help guide resuscitation approaches using immunologic markers of splenic function following burns.
Source: Burns - Category: Dermatology Source Type: research
(Aust N Z J Obstet Gynaecol. 2019;59:45–53) The most common emergency nonobstetric abdominal surgery performed in parturients is appendicectomy, which occurs in ∼0.3% of pregnancies. Establishing the diagnosis of appendicitis is more challenging in pregnant women as a result of the physiological changes of pregnancy and the many non-specific symptoms experienced during normal pregnancy. In addition, the use of ultrasound to make the diagnosis is less effective due to the presence of the gravid uterus and computed tomography scanning is sometimes avoided to prevent fetal radiation exposure. Appendiceal perforatio...
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Epidemiologic Reports Surveys Source Type: research
BackgroundWhether spontaneous breathing (SB) should be used in early acute respiratory distress syndrome (ARDS) is questioned because it may cause ventilator-induced lung injury (VILI) by tidal high strain/stress and recruitment/derecruitment (R/D). However, SB has shown beneficial effects when used appropriately. We hypothesized that high levels of positive end-expiratory pressure (PEEP), during assisted SB, would prevent tidal R/D, reducing ventilatory variation and respiratory rate while potentially increasing transpulmonary pressure (PTP). The aim was to test this hypothesis in experimental mild ARDS during continuous ...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Recently, we identified a wider metabolic reprogramming in lung tissue in a rodent model of PAH [Front Cardiovasc Med 2018: 5: 110]. Specifically, aberrant choline metabolism was identified as a feature of cell proliferation, representing a new therapeutic target for PAH. The aim of this study is the in-vivo monitoring of choline metabolism in a rat model of PAH by Positron Emission Tomography (PET) imaging.Methods: PAH was induced in male Sprague Dawley rats (MCT group) by a single injection of Crotaline (C2401, Sigma-Aldrich). Three weeks after administration, MCT and controls rats were subjected to [11C]Choline PET imag...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Pulmonary hypertension Source Type: research
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