Temporal Modulation of HER2 Membrane Availability Increases Pertuzumab Uptake and Pretargeted Molecular Imaging of Gastric Tumors

Conclusion: Temporal pharmacological modulation of membrane HER2 may be clinically relevant and exploitable for pretargeted molecular imaging and therapy in gastric tumors.

Source: Journal of Nuclear Medicine - October 31, 2019 Category: Nuclear Medicine Authors: Pereira, P. M. R., Mandleywala, K., Ragupathi, A., Carter, L. M., Goos, J. A. C. M., Janjigian, Y. Y., Lewis, J. S. Tags: Basic Source Type: research