Comparison of negative-pressure incision management system in wound dehiscence: A prospective, randomized, observational study.

In this study, it was aimed to select the best incision management system to keep the incision edges together and prevent wound opening, and infection by protecting the incision. In this study, 60 patients who underwent abdominal surgery were evaluated regarding their risk of wound dehiscence. In our clinic, high-risk cases of abdominal surgery are performed, the risk factors being ischemia along the incision line, dirty and contaminated wound, obesity, tension on the suture line, traumatization of the wound site, age at onset (> 65), body mass index (BMI)> 30, diabetes mellitus, chronic obstructive pulmonary disease (COPD), immunosuppressive drug users. A prospective study protocol was planned after ASA (American Society of Anesthesiologists) physical status class assignment. Patients were divided into three groups: patients who underwent a postoperative negative-pressure therapy dressing, patients who underwent subcutaneous aspiration drainage, and patients who received standard dressing. The aim of this study was to evaluate the decompensation, surgical site infection, seroma, hospital stay and costs and to evaluate the results in the postoperative period. Sixty patients were randomized (n = 20, for each group). Thirty-one (51%) of the patients were male, and the mean age was 64.3 ± 8.9 (46-85). The mean BMI was 30.45 ± 7.2. There was no statistically significant difference (p≥0.05) between groups in terms of sex, age, and BMI. The ASA score and surg...
Source: Journal of Medicine and Life - Category: General Medicine Tags: J Med Life Source Type: research

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Publication date: Available online 10 December 2019Source: Small Ruminant ResearchAuthor(s): J. Reintke, K. Brügemann, H. Wagner, P. Engel, A. Wehrend, S. KönigAbstractThere is an increasing economic pressure in sheep production. Hence, it is imperative to use all available tools contributing to improvements in lamb survival. In this regard, there is a lack of studies addressing the impact of maternal body condition traits on lamb performances during lactation. Specifically, the focus of the present study was to analyse associations between ewe traits reflecting maternal energy metabolism and lamb body weight (LB...
Source: Small Ruminant Research - Category: Zoology Source Type: research
In this study, AA loading PEGylated nanostructured lipid carriers (P-AA-NLC) were prepared. P-AA-NLC were characterized for particle size distribution, polydispersity index, entrapment efficiency, X-ray powder diffraction pattern (XRD), differential scanning colorimeter (DSC) and transmission electron microscopy (TEM). The intestinal absorption, in vivo distribution, pharmacokinetics and anti-fibrosis effects of P-AA-NLC were studied compared with that of AA-NLC. In situ single-pass intestinal perfusion model shown that there are significant differences in absorption between the free and NLCs formulation. The Peff values o...
Source: Drug Development and Industrial Pharmacy - Category: Drugs & Pharmacology Tags: Drug Dev Ind Pharm Source Type: research
Authors: Morita K, Wang D, Baba R, Morimoto H, Song Y, Kanazawa T, Yoshida Y Abstract Although it is known that desert dust exacerbates allergic diseases, how it affects the onset of autoimmune diseases is unclear. No epidemiological investigations or animal experiments have been conducted so far to elucidate the effects of desert dust on autoimmune diseases. Here, we focused on particulate matter, such Asian sand dust (ASD) that has been known to cause adverse health effects in East Asian countries, and conducted animal experiments to examine how ASD influences type 1 diabetes (T1D), an autoimmune disease. An ASD ...
Source: Immunological Investigations - Category: Allergy & Immunology Tags: Immunol Invest Source Type: research
Applied Physiology, Nutrition, and Metabolism, e-First Articles. We are currently facing an “obesity epidemic” worldwide. Promoting inefficient metabolism in muscle represents a potential treatment for obesity and its complications. Sarco(endo)plasmic reticulum (SR) Ca2+-ATPase (SERCA) pumps in muscle are responsible for maintaining low cytosolic Ca2+ concentration through the ATP-depe ndent pumping of Ca2+ from the cytosol into the SR lumen. SERCA activity has the potential to be a critical regulator of body mass and adiposity given that it is estimated to contribute upwards of 20% of daily energy expenditure....
Source: Applied Physiology, Nutrition, and Metabolism - Category: Physiology Authors: Source Type: research
Analyst, 2019, Accepted Manuscript DOI: 10.1039/C9AN01704F, Critical ReviewSim ão Santos, Tao Dong, Zhaochu Yang, Shuai Yang, Niels Kirkhus Chronic Obstructive Pulmonary Disease (COPD) became one of the most important diseases of the century, considering the mortality and morbidity levels worldwide. This disease is an inflammatory response to environmental... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - Category: Chemistry Authors: Source Type: research
POSTOPERATIVE PAIN AND STRESS RESPONSE: DOES CHILD'S GENDER HAVE AN INFLUENCE? Acta Clin Croat. 2019 Jun;58(2):274-280 Authors: Karišik M, Gligorović Barhanović N, Vulović T, Simić D Abstract Surgical procedure causes multisystem stress response reactions. The aim of this study was to assess whether gender has an impact on the level of neuroendocrine response to surgical stress and intensity of postoperative pain in children undergoing inguinal hernia repair surgery, as well as satisfaction of their parents with preoperative and postoperative care. The study included 60 children aged 3-6 yea...
Source: Acta Clinica Croatica - Category: General Medicine Tags: Acta Clin Croat Source Type: research
Authors: Štubljar D, Štefin M, Tacar MP, Cerović O, Grosek Š Abstract Delirium is a clinical syndrome often underestimated in the intensive care units (ICU). The aim of this study was to determine the prevalence and factors that influence the onset of delirium. A questionnaire was sent to intensivists in Slovenian ICUs, who estimated the prevalence of delirious patients. The questionnaire consisted of demographic data, type of ICU, diagnosis, reason for admission to the ICU, type of anesthesia and surgery, clinical condition, type of supportive therapy, presence of delirium, data on discharge,...
Source: Acta Clinica Croatica - Category: General Medicine Tags: Acta Clin Croat Source Type: research
This study describes the nutritional status of Qom preschoolers in general, and by neighborhood area and family's socioeconomic characteristics in a peri-urban village of Formosa, Argentina. Across-sectional study was carried out between January and December 2016, with 160 Qom children between 2 and 5 years of age. Interviews and anthropometric measures were conducted at the children's homes. Nutritional status was determined by body mass index. The prevalence of excess weight (overweight + obesity) and of stunting were associated with neighborhood area and socioeconomic level. The overall prevalence of stunting was 15.6% ...
Source: Ecology of Food and Nutrition - Category: Nutrition Tags: Ecol Food Nutr Source Type: research
Authors: Singh AK, Singh R Abstract BACKGROUND: Lorcaserin is a novel, selective 5-hydroxytryptamine 2C serotonin receptor agonist, approved for the treatment of obesity. Several phase 3 randomized controlled trials (RCTs) trials have shown a significant reduction in body weight with lorcaserin. RESEARCH DESIGN AND METHODS: We systematically searched the database of PubMed, Embase, The Cochrane Library and ClinicalTrials.gov up to July 31, 2019 and retrieved all the studies conducted with lorcaserin for ≥ 1-year that have explicitly reported the efficacy and safety outcomes versus placebo. Subsequently, we s...
Source: Expert Review of Clinical Pharmacology - Category: Drugs & Pharmacology Tags: Expert Rev Clin Pharmacol Source Type: research
Authors: Umapathy S, Thulasi R, Gupta N, Sivanadhan S Abstract The aim and objectives of this study were as follows: (i) to perform automated segmentation of knee thermal image using the regional isotherm-based segmentation (RIBS) algorithm and segmentation of ultrasound image using the image J software; (ii) to implement the RIBS algorithm using computer-aided diagnostic (CAD) tools for classification of rheumatoid arthritis (RA) patients and normal subjects based on feature extraction values; and (iii) to correlate the extracted thermal imaging features and colour Doppler ultrasound (CDUS) features in the knee re...
Source: Biomedizinische Technik/Biomedical Engineering - Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research
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