Effectiveness of single-dose rifampicin after BCG vaccination to prevent leprosy in close contacts of patients with newly diagnosed leprosy: A cluster randomized controlled trial

The global number of new leprosy cases has remained stable over the last decade (Anonymous, 2017a), indicating that transmission of Mycobacterium leprae, the causative agent of leprosy, is ongoing in many endemic countries. The basic intervention in leprosy control is multidrug therapy (MDT), but this appears insufficient to decrease new cases numbers and achieve the World Health Organization (WHO) target of reducing the burden of leprosy (Anonymous, 2018).

Source: International Journal of Infectious Diseases - September 5, 2019 Category: Infectious Diseases Authors: Renate Richardus, Khorshed Alam, Kallyan Kundu, Johan Chandra Roy, Tasnuva Zafar, Abu Sufian Chowdhury, Daan Nieboer, Roel Faber, C. Ruth Butlin, Annemieke Geluk, Jan Hendrik Richardus Source Type: research