Sars-like illness kills man in London

Qatari man who was transferred to UK by air ambulance last September had Middle East respiratory syndrome coronavirusA man infected with a Sars-like respiratory illness has died in London, officials say.The Qatari man, who was being treated in an intensive care unit at St Thomas's hospital in central London, had contracted the Middle East respiratory syndrome coronavirus – or Mers-CoV.Hospital officials said the man, who was 49 when he was admitted, died after his condition deteriorated.The patient, who was suffering from acute respiratory syndrome and renal failure, was admitted to an intensive care unit in Doha, Qatar, on 7 September last year. The man, who has not been named by officials, was transferred to the UK by air ambulance on 11 September. Before he became ill he had travelled to Saudi Arabia, officials said.Despite doctors' efforts to keep him alive, including connecting him to an artificial lung, he died on Friday last week.A hospital spokeswoman said: "Guy's and St Thomas's can confirm that the patient with severe respiratory illness due to novel coronavirus … sadly died on Friday 28 June, after his condition deteriorated despite every effort and full supportive treatment."In May, the World Health Organisation (WHO) said Mers-CoV was a "threat to the entire world" and experts have raised concerns that the disease is "emerging faster than our understanding".Latest figures from the WHO, published before the latest UK...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: World news Infectious diseases guardian.co.uk Medical research Microbiology UK news Sars Science Source Type: news

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Authors: Manfredi EA, Rivas M Abstract On November 27, 2008, a foodborne disease outbreak associated with the consumption of chicken salad occurred in a kindergarten in the District of Hurlingham, Province of Buenos Aires. Thirty-seven children and 10 adults with gastrointestinal symptoms were affected. Five children were hospitalized with signs of dehydration, one of them requiring intensive care. Staphylococcus aureus subsp. aureus was isolated from the mentioned food in 4 out of 5 stool specimens from the patients, and in 3 out of 5 food handlers (nose of food handler #1, hands of food handlers #2 and 3). The is...
Source: Revista Argentina de Microbiologia - Category: Microbiology Tags: Rev Argent Microbiol Source Type: research
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Source: Epidemics - Category: Epidemiology Source Type: research
A 6-month-old boy presented with acute renal failure, thrombocytopenia, and severe non-immune hemolytic anemia. Infection by Shiga-like toxin-producingEscherichia coli and other causes of microangiopathic hemolysis were ruled out, leading to a diagnosis of atypical hemolytic uremic syndrome (aHUS). Neither pathogenic variants in HUS-associated genes nor anti-factor H antibodies were identified. Copy number variation analysis uncovered 4 copies of complement factor H related genes,CFHR1-CFHR4, conceivably leading to higher than normal levels of the corresponding proteins. However, this abnormality was also found in the heal...
Source: Nephron - Category: Urology & Nephrology Source Type: research
In this study, we predicted an influenza-like illness (ILI) based on social media data derived from Twitter. Tweets and patients do not always have a linear correlation; therefore, we employed nonlinear methods including autoregressive with exogenous inputs (ARX), autoregressive-moving-average with exogenous inputs (ARMAX), nonlinear autoregressive exogenous (NARX), deep multilayer perceptron (DeepMLP), and a convolutional neural network (CNN). Two new features employed to significantly reduce the prediction errors are products of the tweets and Centers for Disease Control and Prevention (CDC) data and of the tweets and Go...
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We report the case of an adolescent with an HHV6-related MERS presenting with hyponatremia and urinary and fecal retention. To our knowledge, urinary retention is not a constant aspect of the disease and has rarely been described, while fecal retention has never been reported before. Despite the self-limiting nature of the disease, it is mandatory to suspect it for a faster diagnosis and it might be useful to know its rare occurrences in order to better understand its etiopathogenetic mechanisms. PMID: 30882387 [PubMed - in process]
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Authors: Ceylan B, Yilmaz M, Beköz HS, Ramadan S, Ertan Akan G, Mert A Abstract Invasive aspergillosis is a severe infection that generally involves the lungs. Primary gastrointestinal aspergillosis is the least common form of invasive aspergillosis. A patient aged 65 years developed a febrile neutropenic episode following an autologous stem cell transplant for plasmacytoid variant diffuse large B-cell gastric non-Hodgkin's lymphoma. He had abdominal pain on the second day of the febrile neutropenic episode and ileus occurred on the sixth day. His general condition deteriorated despite broad spectrum antibioti...
Source: Infezioni in Medicina - Category: Infectious Diseases Tags: Infez Med Source Type: research
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Authors: Deng F, Zhang J, Li Y, Wang W, Hong D, Li G, Feng J Abstract Immunoglobulin A nephropathy (IgAN) is characterized by mesangial IgA and IgG co-deposition. As the clinical course of IgAN is highly variable, a lot of patients will eventually develop to end-stage renal disease (ESRD) within years. Hirudin, a potent and specific thrombin inhibitor, has been reported to treat IgAN with hematuria, but the mechanism is unclear. Our study aims to explore the potential of hirudin and the underlying mechanism in the treatment of IgAN. The establishment of IgAN model was set up in rats through oral and intravenous imm...
Source: Renal Failure - Category: Urology & Nephrology Tags: Ren Fail Source Type: research
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