Predictors of All-Cause Mortality after Endovascular Aneurysm Repair: Assessing the Role of Psoas Muscle Cross-Sectional Area

Publication date: Available online 30 October 2019Source: Journal of Vascular and Interventional RadiologyAuthor(s): Timothy C. Huber, Nicole Keefe, James Patrie, Margaret C. Tracci, Daniel Sheeran, John F. Angle, Luke R. WilkinsAbstractPurposeTo evaluate psoas muscle area (PMA) as a predictor of all-cause mortality after endovascular aneurysm repair (EVAR) and compare it with other predictor variables.Material and MethodsRetrospective review of 407 patients who underwent EVAR over a 7-year period was performed. Demographics, comorbidity variables, and outcomes were collected. Preprocedure computed tomography scans were used to measure the PMA. Descriptive statistics summarized the demographic information and predictor variables. Kaplan-Meier analysis and univariate and multivariate Cox proportional regression analyses were performed. The main outcome measure was survival time.ResultsMedian survival time for patients with PMA in the lowest quartile of the distribution (≤1442 mm2) was 65.5 months (95% confidence interval [95% CI] 37.7–78.9) vs 91.2 months (95% CI 77.9–110.0 when PMA>1442 mm2). Multivariate analysis revealed lower PMA was associated with decreased survival (adjusted hazard ratio [AHR] 1.68; 95% CI 1.15–2.40, P = .006). Similarly, the presence of coronary artery disease (AHR 1.54, 95% CI 1.01–2.35, P = .045) and statin use after EVAR were associated with decreased survival (AHR 2.36, 95% CI 1.24–4.49, P = .009)....
Source: Journal of Vascular and Interventional Radiology - Category: Radiology Source Type: research

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